The undefeated No. 2 Iowa State Cyclones aim to remain perfect as they hit Allen Fieldhouse to face the Kansas Jayhawks in Big 12 play tonight.
This is the best T.J. Otzelberger squad we’ve seen, which is why my Iowa State vs. Kansas predictions expect the Cyclones to win in Lawrence for the first time since 2017.
Read all about it in my college basketball picks for January 13.
Iowa State vs Kansas prediction
Iowa State vs Kansas best bet: Iowa State -4 (-110)
The Iowa State Cyclones have established themselves as a legitimate National Championship contender through the first half of the season, sitting pretty with a 16-0 record.
They’re currently third overall in KenPom and are deadly on both ends of the court, ranking 12th in adjusted efficiency on offense and second on defense.
While the road trip to Lawrence is never fun, the Cyclones have played well in both road games, beating Purdue and Baylor by double digits.
This isn’t your typical Kansas Jayhawks team, as Bill Self’s 11-5 squad fell out of the rankings after an 11-point loss to West Virginia moved them to 1-2 in conference play. They have a -1.2 turnover margin, which is a major issue against the disruptive Cyclones (+6.7 TO margin).
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Iowa State vs Kansas same-game parlay
These two teams have been on a crash course to the Under when playing each other, going 1-8 O/U in the last nine meetings.
Kansas’ defense likes to push opponents toward the perimeter (331st in opponent three-point attempts per game), which should open up looks for sharp shooter Milan Momcilovic. The junior forward has been scorching nets, averaging 3.8 triples per game.
Iowa State vs Kansas SGP
- Iowa State -4
- Under 148
- Milan Momcilovic Over 2.5 threes
Our beyond the arc SGP: Darryn to believe
Darryn Peterson is playing over 30 minutes, is averaging 3.1 threes per game, and has cashed the Over in all three games at Phog.
Iowa State vs Kansas SGP
- Iowa State -4
- Under 148
- Milan Momcilovic Over 2.5 threes
- Darryn Peterson Over 2.5 threes
Iowa State vs Kansas odds
- Spread: Iowa State -3.5 | Kansas +3.5
- Moneyline: Iowa State -170 | Kansas +145
- Over/Under: Over 151.5 | Under 151.5
Iowa State vs Kansas betting trend to know
Iowa State is 5-1 ATS away from home this season. Find more college basketball betting trends for Iowa State vs. Kansas.
How to watch Iowa State vs Kansas
| Location | Allen Fieldhouse, Lawrence, KS |
| Date | Tuesday, January 13, 2026 |
| Tip-off | 9:00 p.m. ET |
| TV | ESPN |
Iowa State vs Kansas key injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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