The Detroit Tigers are -145 favorites in their series finale against the New York Yankees.
With Tarik Skubal on the mound, my Yankees vs. Tigers predictions and MLB picks are backing the home team to come out on top in the rubber match.
Who will win Yankees vs Tigers today: Tigers (-145)
Ryan Weathers has allowed at least five runs in four of his past six starts, conceding 10 homers along the way. Only once did he avoid a longball during that stretch.
The Detroit Tigers rank 15th in ISO against left-handed pitching, so they have enough power to cause problems for Weathers.
Tarik Skubal owns a sparkling 2.74 xFIP on the season and has effectively limited walks and homers. While the New York Yankees generally excel against lefties, they’re missing a lot of key bats due to injury.
Expect Skubal to capitalize and back the Tigers to -150.
COVERS INTEL: Weathers has allowed an 11.7% barrel rate, ranking him in the eighth percentile.
Yankees vs Tigers Over/Under pick: Over 7.0 (-120)
This total is half a run too low.
Homers are a great way to get chunk production, and Weathers is having a miserable time limiting them.
The Tigers rank eighth in ISO and first in flyball rate against lefties in June, so they’re well equipped to put Weathers’ home-run struggles to the test.
Skubal is one of the marquee pitchers in the sport, but he hasn’t been as effective this season while fighting injuries — understandably so.
He ranks in the 32nd percentile in hard hit rate and has allowed multiple runs in four straight starts.
Play to -130.
- ML/RL bets: 40-29, +3.0 units
- Over/Under bets: 36-29-4, +3.59 units
Yankees vs Tigers weather
Temperatures are expected to hover around 70 degrees with winds blowing in close to 10 mph. The weather favors the pitchers slightly, but the weather shouldn't be very impactful.
Yankees vs Tigers odds
- Moneyline: Yankees +125 | Tigers -145
- Run line: Yankees +1.5 (-170) | Tigers -1.5 (+145)
- Over/Under: Over 7.0 (-120) | Under 7.0 (+100)
Yankees vs Tigers trend
Detroit owns a 22-17 record on home soil this season. Find more MLB betting trends for Yankees vs. Tigers.
How to watch Yankees vs Tigers and game info
| Location | Comerica Park, Detroit, MI |
| Date | Wednesday, June 24, 2026 |
| First pitch | 6:40 p.m. ET |
| TV | Prime Video |
| Yankees starting pitcher | Ryan Weathers (2-5, 4.13 ERA) |
| Tigers starting pitcher | Tarik Skubal (3-3, 3.02 ERA) |
Yankees vs Tigers latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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