The New York Yankees are -160 road favorites against the Washington Nationals, and I’m laying the run line behind a clear power edge.
Washington’s opener-bulk setup points toward Zack Littell carrying the meaningful innings, and his profile is a poor fit against a Yankees offense built around long-ball damage.
Here are my Yankees vs. Nationals predictions and MLB picks for July 10.
Who will win Yankees vs Nationals today: Yankees -1.5 (+100)
I’m laying the New York Yankees run line because the Washington Nationals still need Zack Littell to carry the meaningful innings after Carson Palmquist opens. The issue is not just damage allowed, it's how little swing-and-miss Littell has behind it.
His 14.1% strikeout rate and 17.1% whiff rate are both well below MLB average, while hitters make 89% zone contact against him.
Against a Yankees lineup that leads baseball in homers, that many balls in play creates the best margin path.

Yankees vs Nationals Over/Under pick: Over 10 (-105)
I’m playing the Over for two units and would take it to -160. I made this total 11.2.
I’ve been waiting to see Littell face this Yankees offense. Aaron Judge being out and Littell having opener cover make it less clean, but the matchup is still brutal. Littell has a 6.53 xERA, 11% barrel rate, and 65% air-ball rate against a homer-dependent Yankees lineup.
Ryan Weathers brings similar barrel risk, allowing 10.8% barrels against a Nationals lineup with a Top-10 barrel rate and 132 homers.
- ML/RL bets: 37-33, +6.22 units
- Over/Under bets: 42-30, +16.06 units
Yankees vs Nationals weather
Warmer weather typically favors offense, and it will be above 80F at first pitch with minimal wind or rain to speak of.
Yankees vs Nationals odds
- Moneyline: Yankees -160 | Nationals +135
- Run line: Yankees -1.5 (+100) | Nationals +1.5 (-155)
- Over/Under: Over 10 | Under 10
Yankees vs Nationals trend
The Nationals have hit the Over in 32 of their last 50 games at home (+15.70 Units / 29% ROI)
How to watch Yankees vs Nationals and game info
| Location | Nationals Park, Washington, D.C. |
| Date | Friday, July 10, 2026 |
| First pitch | 7:45 p.m. ET |
| TV | FOX |
| Yankees starting pitcher | Ryan Weathers (3-7, 4.29 ERA) |
| Nationals starting pitcher | Zack Littell (7-6, 5.02 ERA) |
Yankees vs Nationals latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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