The Chicago Cubs (-170) are coming off a thrilling extra-innings victory, and they're in a good spot to grab another win tonight against the Chicago White Sox.
They have Kevin Gausman on the mound going up against a steady stream of relievers, making the home team an attractive buy with my White Sox vs. Cubs predictions and MLB picks on Tuesday, Aug. 18.
Who will win White Sox vs Cubs today: Chicago Cubs (-170)
Kevin Gausman has pitched better than the results indicate over the past month.
He’s held opponents to a 31.1% hard-hit rate — third-lowest among today’s projected starters — and has a 0.68 HR/9, but hasn’t kept runs off the board in part due to an unsustainably high .364 BABIP and a low 61.8% strand rate.
He’s in a good spot to rebound against the Chicago White Sox. They’ve hit .233 against righties in August while striking out 27.4% of the time.
The Chicago Cubs should give him plenty of support against a bullpen sitting 22nd with a 4.70 xFIP this month.
Play to -180.
COVERS INTEL: The Cubs rank second in homers and third in HR/FB at home over the last month.
White Sox vs Cubs Over/Under pick: Over 8.5 (-126)
The White Sox have gotten five innings out of their starter just once over the past five games, putting a lot of strain on their relievers.
That’s far from ideal heading into a designated bullpen game where nine innings are needed from a group in poor form.
The Cubs rank third in wOBA and first in ISO in August, and are certainly capable of making life difficult on this bullpen.
While the White Sox haven’t hit for average, they do have power that should play well at Wrigley with winds blowing out.
Take to -135.
White Sox vs Cubs home run prediction: Munetaka Murakami (+245)
There are no secrets when facing Gausman. You’re going to see a ton of fastballs, and you’re going to see a ton of splitters.
Munetaka Murakami hasn’t faced many splitters this season, but he has absolutely destroyed the fastball against right-handed pitching.
He owns a ridiculous 27.5% barrel rate, 62.5% hard-hit rate, and .436 ISO. He is likely to sit on the fastball, and it only takes one good swing to do damage – especially with the predicted 15% home run boost with help from the wind at Wrigley.
Back to +230.
- ML/RL bets: 82-74, -8.85 units
- Over/Under bets: 83-67-6, +5.98 units
White Sox vs Cubs weather
The forecast calls for temperatures in the mid-70s with up to 10 mph winds blowing out. While there could be some rain, the bats will see a boost.
White Sox vs Cubs odds
- Moneyline: White Sox +145 | Cubs -170
- Run line: White Sox +1.5 (-135) | Cubs -1.5 (+115)
- Over/Under: Over 9.0 (-105) | Under 9.5 (-115)
White Sox vs Cubs trend
The Cubs have won 33 of their last 50 games (+11.65 units, 18% ROI). Find more MLB betting trends for White Sox vs. Cubs.
How to watch White Sox vs Cubs and game info
| Location | Wrigley Field, Chicago, Ill. |
| Date | Tuesday, Aug. 18, 2026 |
| First pitch | 8:05 p.m. ET |
| TV | TBS |
| White Sox starting pitcher | Bryan Hudson (3-4, 3.14 ERA) |
| Cubs starting pitcher | Kevin Gausman (6-11, 4.53 ERA) |
White Sox vs Cubs latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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