There aren't many chances left to find Spring Training betting edges, with today being the final Saturday of exhibition play.
My MLB picks have scoured the board to find the best bets to make on March 21.
See why the White Sox top my trio of road team moneylines for today.
Spring Training predictions for March 21
| Pick | Odds |
|---|---|
 COL moneyline |
+135 |
 SD moneyline |
-110 |
 CHW moneyline |
+105 |
Pick #1: Rockies moneyline
This is a pitching mismatch based on Cactus League results.
Colorado Rockies SP Kyle Freeland has bounced back nicely from a dismal 2025, authoring a 1.80 ERA through five innings this spring. He was last seen blanking the Chicago Cubs over three frames.
Cole Ragans counters for the Kansas City Royals, and he enters play with a monstrous 8.44 ERA. He's surrendered 14 hits over 10 2/3 innings, and has allowed at least two ER in three straight appearances.
Pick #2: Padres moneyline
The San Diego Padres bring the better record into this one, sporting a 14-13 mark compared to the Milwaukee Brewers' 11-15 record.
The Padres also have the better of the two starters going for them today in Randy Vasquez. He's pitched to a 4.15 ERA so far, fanning 11 batters over 8 2/3 innings.
Meanwhile, Robert Gasser totes a 9.95 ERA into this one. He's allowed three homers in just 5 1/3 innings of work.
Pick #3: White Sox moneyline
The Chicago White Sox are on the long end of what's arguably the biggest starting pitching mismatch of the day, yet they are underdogs. Sign me up.
Ryan Borucki rocks a 2-0 record with a spotless ERA. He's allowed only four hits and a walk while striking out five batters over four frames.
Cincinnati Reds SP Andrew Abbott looks ready for regression after an incredible 2025 campaign. He's 1-3 with a 13.85 ERA in Cactus League action, allowing 18 ER over 11 frames.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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