The Milwaukee Brewers host the Boston Red Sox in the third and final matchup of this series at American Family Field. MLB odds list Milwaukee as a -155 favorite, while the total sits at 7.5.
My Red Sox vs. Brewers prediction targets the home side in this interleague matchup.
Read on for my MLB picks for Wednesday, May 28.
Red Sox vs Brewers prediction
My Red Sox vs Brewers best bet: Brewers moneyline (-155 at DraftKings)
The clear pitching advantage in this contest goes to the Milwaukee Brewers. Staff ace Freddy Peralta, a right-hander, takes the mound and is a strong candidate to back.
Since transitioning to a starting role in 2021, Peralta has produced a 42-31 record with a 3.40 ERA and 1.10 WHIP. That success has continued into 2025.
Through 11 starts this season, the right-hander owns a 5-3 record with a 2.55 ERA and 1.12 WHIP. His underlying metrics suggest that this level of performance is sustainable.
Peralta ranks in the top third of the league in expected batting average (xBA), average exit velocity, strikeout rate, and hard-hit rate.
Brayan Bello gets the ball for the Boston Red Sox. He has struggled to find consistency since making his MLB debut in 2022, posting a 4.39 ERA and 1.44 WHIP across four seasons.
His analytics are particularly poor this year. Entering this matchup, Bello ranks in the 10th percentile or lower in expected ERA (xERA), xBA, chase rate, and walk rate.
Red Sox vs Brewers same-game parlay (SGP)
Brewers moneyline
Christian Yelich 1+ hits
Jackson Chourio 1+ hits
If Milwaukee is going to win this game, it will need production at the plate. Two of the best candidates to deliver are Christian Yelich and Jackson Chourio.
Yelich played the hero in last night’s game, hitting a walk-off grand slam in extra innings. He is also 2-for-5 in his career against Bello.
Meanwhile, Chourio has recorded 10 hits over his past eight games and owns a .303 batting average in that stretch.
Red Sox vs Brewers odds
Red Sox vs Brewers live odds
Red Sox vs Brewers opening odds
- Moneyline: Boston +130 | Milwaukee -155
- Run line: Boston +1.5 (-160) | Milwaukee -1.5 (+135)
- Over/Under: Over 7.5 (-120) | Under 7.5 (+100)
Red Sox vs Brewers trend
Milwaukee has won four of the past five meetings between these two teams. Find more MLB betting trends for Red Sox vs. Brewers.
How to watch Red Sox vs Brewers and game info
| Location | American Family Field, Milwaukee, WI |
| Date | Wednesday, 5-28-2025 |
| First pitch | 1:10 p.m. ET |
| TV | NESN, FanDuel Sports Network Wisconsin |
| Red Sox starting pitcher | Brayan Bello (2-1, 4.08 ERA) |
| Brewers starting pitcher | Freddy Peralta (5-3, 2.55 ERA) |
Red Sox vs Brewers latest injuries
Red Sox vs Brewers weather
Odds are correct at the time of publishing and are subject to change.
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