The Texas Rangers were shut out by the Houston Astros on Friday night, falling 2-0.
However, with Jacob deGrom taking the mound this evening, my Rangers vs. Astros predictions expect the visitors to flip the script at Daikin Park.
Let's dive deeper into my MLB picks for Saturday, May 16.
Who will win Rangers vs Astros today: Rangers (-145)
Jacob deGrom has posted a 2.81 xFIP and 2.60 SIERA in 2026, indicators that he is every bit deserving of his strong 2.61 ERA.
The Texas Rangers' right-hander has not allowed much quality contact, striking out a remarkable 32.8% of opposing batters on the year.
Now, the two-time Cy Young winner has a mouthwatering matchup against the Houston Astros, who rank 23rd in wOBA and own the second-highest strikeout rate vs. right-handed pitching in May.
DeGrom will have his way against Houston's struggling offense, giving Texas a great chance of prevailing.

Rangers vs Astros Over/Under pick: Under 8 (-120)
Generating offense has been a major problem for the Astros, with several key bats missing from the lineup. They have hit their team total Under in 13 of the last 15 games (+10.35 units, 55% ROI), and a date with deGrom is only going to highlight their woes at the plate — especially when it comes to striking out.
The Rangers aren't exactly firing on all cylinders either. They are hitting only .216 in May and own the fifth-highest ground ball rate, leading to a lot of easy outs.
Don't expect fireworks in this one.
- ML/RL bets: 17-10, +3.48 units
- Over/Under bets: 11-15-1, -6.41 units
Rangers vs Astros odds
- Moneyline: Rangers -145 | Astros +125
- Run line: Rangers -1.5 (+115) | Astros +1.5 (135)
- Over/Under: Over 8 (+100) | Under 8 (-125)
Rangers vs Astros trend
Texas has hit the game total Under in 17 of its last 25 games (+8.4 Units, 31% ROI). Find more MLB betting trends for Rangers vs. Astros.
How to watch Rangers vs Astros and game info
| Location | Daikin Park, Houston, TX |
| Date | Saturday, May 16, 2026 |
| First pitch | 7:10 p.m. ET |
| TV | RSN, Space City HN |
| Rangers starting pitcher | Jacob deGrom (3-2, 2.62 ERA) |
| Astros starting pitcher | Kai-Wei Teng (1-3, 3.12 ERA) |
Rangers vs Astros latest injuries
Rangers vs Astros weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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