Going down to the wire for the American League East crown, the New York Yankees look to make it seven straight wins when they battle the Baltimore Orioles this afternoon.
The Yankees are deadlocked with the Blue Jays with identical 92-68 records, with Toronto holding the tiebreaker.
Our Orioles vs Yankees predictions and MLB picks have New York staying hot against Baltimore on Saturday, September 27.
Orioles vs Yankees prediction
Orioles vs Yankees best bet: Yankees -1.5 (-110)
The scheduling gods have gifted the New York Yankees a soft stretch coming home, and they’ve taken full advantage.
Going against the AL Central’s two worst teams in Minnesota and Chicago, and six against the AL East basement-dwelling Baltimore Orioles, New York has ripped off wins in nine of its last 11.
With an 8-4 win to open the set against Baltimore, it’s just the second time during this six-game fun run New York has allowed more than two runs in a game. The Yankees also won by at least two runs in each of their last five victories against Baltimore.
They turn to righty Cam Schlittler today, and he should know his opponent fairly well, making consecutive starts against the O’s. Schlittler held Baltimore to just three hits and one earned run in 5 1/3 innings, while striking out six.
The Orioles have dropped five of eight and turn to righty Tomoyuki Sugano on the mound. He also last pitched against the Yankees and was shelled, getting chased after three innings, allowing six hits and four earned runs.
He’s struggled of late, losing four times in five starts, and carrying a 6.00 ERA in September. Now is not the time to be slumping. The Yankees are hitting .333 off Sugano this year, with three homers and seven runs batted in.
With the stakes extra high, New York keeps the pedal to the metal to chase down that AL East crown.
Orioles vs Yankees same-game parlay (SGP)
Aaron Judge homered and drove in a couple in Friday's opener, and has now grabbed at least two total bases in three straight games.
He has also feasted off Sugano, going 6-for-7 this season, with two homers and two RBI.
Let’s wrap with Schlitter, who is tabbed with a 6.5 strikeout line, which he has topped just once in four September starts.
Baltimore will get its second look at him, which will be to its advantage. Schlittler should come close, but take the Under to prevail here.
Orioles vs Yankees SGP
- Yankees -1.5
- Aaron Judge Over 1.5 total bases
- Cam Schlittler Under 6.5 strikeouts
Orioles vs Yankees odds
- Moneyline: Baltimore +185 | New York -225
- Run line: Baltimore +1.5 (-110) | New York -1.5 (-110)
- Over/Under: Over 9 (+100) | Under 9 (-120)
Orioles vs Yankees trend
New York has won seven straight home games vs teams with a losing record. Find more MLB betting trends for Orioles vs. Yankees.
How to watch Orioles vs Yankees and game info
| Location | Yankee Stadium, Bronx, NY |
| Date | Saturday, September 27, 2025 |
| First pitch | 1:05 p.m. ET |
| TV | MASN, YES, MLBN |
| Orioles starting pitcher | Tomoyuki Sugano (10-9, 4.54 ERA) |
| Yankees starting pitcher | Cam Schlittler (3-3, 3.27 ERA) |
Orioles vs Yankees latest injuries
Orioles vs Yankees weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
