MLB Predictions and Moneyline Picks for Thursday, September 10

Phil Naessens - Contributor at Covers.com
Phil Naessens • Betting Analyst 19+ years betting experience
Updated: Sep 10, 2026 , 03:27 AM ET • 4 min read

The White Sox beating the Pirates as 50% favorites highlights our Thursday's MLB moneyline predictions.

Hagen Smith of the Chicago White Sox MLB
Photo By - Reuters Connect. Hagen Smith of the Chicago White Sox MLB

Our Thursday MLB moneyline predictions feature several intriguing individual and team matchups, with plenty of value available across today's five-game slate.

Read on for my MLB moneyline predictions and MLB picks for Thursday, Sept. 10.

MLB moneyline picks for September 10

For help understanding Polymarket probabilities, see our odds calculator.

Matchup Pick
Rays Rays
vs
Braves Braves
Braves
53%
Astros Astros
vs
Phillies Phillies
Astros
38%
Rangers Rangers
vs
Mariners Mariners
Rangers
46%
Rockies Rockies
vs
Yankees Yankees
Rockies
26%
Pirates Pirates
vs
White Sox White Sox
White Sox
50%

Prices courtesy of Polymarket as of September 10.

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Expert MLB moneyline picks for September 10

Rays vs Braves:  Braves

Braves win probability: 53.9%

Atlanta has the edge here, mainly because of what happens after the starters leave.

Nick Martinez and Martín Pérez are both serviceable enough, so this game could easily swing in the later innings.

That is where Atlanta separates. Over the last two weeks, Tampa Bay’s bullpen owns a 4.45 SIERA with just an 8.5% K-BB rate, while Atlanta has been much sharper at 3.88 with a 1.15 WHIP and a 14.0% K-BB rate.

If this is close late, the Braves are in the better spot.

Astros vs Phillies: Astros

Astros win probability: 38%

This one comes down to whether Philadelphia’s current price matches the way its offense is playing, and right now it does not.

The Phillies have posted a 79 wRC+ with a .297 OBP over the last two weeks, which is well below what you would expect from a team carrying this kind of number.

Zack Wheeler is the clear headliner, but Houston still has some swing-and-miss upside with Cristian Javier, and the Astros bullpen has been solid with a 3.11 FIP over that same stretch.

The gap between these teams is not as wide as the number suggests.

Rangers vs Mariners: Rangers

Rangers win probability: 46%

Texas looks live here for two reasons: Jacob deGrom and the lineup's recent form.

Seattle has struck out 26.4% of the time over the last two weeks and has managed just a 93 wRC+ in that span.

Texas, meanwhile, has been one of the better offenses in baseball lately, ranking third with a 122 wRC+ and backing it up with a strong .204 ISO.

Logan Gilbert is good enough to keep Seattle competitive, but Texas has the hotter bats and the more dangerous starter.

Rockies vs Yankees: Rockies

Rockies win probability: 26%

The Yankees are the obvious favorite, but recent offensive form doesn't fully support such a steep number.

Over the last two weeks, New York has produced a 107 wRC+, but the .128 ISO stands out because the power has not really been there.

Colorado has actually been more competitive at the plate than people might expect, putting up a 101 wRC+ with a .349 OBP in that same stretch.

Max Fried is the biggest difference-maker in this matchup, but if the question is whether New York has earned this big of a gap, the recent numbers say not really.

Pirates vs White Sox: White Sox

White Sox win probability: 52%

Chicago has quietly been better offensively than Pittsburgh lately, and that is the biggest reason this matchup leans their way.

Over the last two weeks, the White Sox own a 111 wRC+ and have paired it with an excellent 12.9% walk rate.

Pittsburgh has remained one of the weaker offenses in this group, posting an 85 wRC+ with a .101 ISO.

Chicago’s bullpen has also been excellent, recording a 2.10 ERA and a 15.9% K-BB rate over that stretch.

Jared Jones can change the shape of any game, but the recent team form points toward the White Sox.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Phil Naessens
Betting Analyst

Prior to joining Covers in 2022, Phil Naessens spent 38 years as a resident tennis pro in Las Vegas, Mykonos, and Corfu, Greece. He’s the past host of the Phil Naessens Show (Armed Forces Radio), and currently hosts the Crush and Rush Tennis Podcast.

Phil is the author of the Betting 101 series (MLB, NFL, NCAAF, and Tennis) and has written for numerous publications, including Advance Local, SB Nation, FanSided, and Lenny Melnick Fantasy Sports. 

His favorite sports to bet on are tennis, MLB, WNBA, Euro men’s and women’s hoops, NCAA sports, NFL, and the NBA. Phil has numerous betting accounts in the US and Europe, and his best advice is to line shop for the best value possible.

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