The Seattle Mariners will either clinch a World Series spot when they face the Toronto Blue Jays in Game 6, or the Jays will send this to a seventh and decisive matchup.
With all eyes on Sunday night's matchup at the Rogers Centre, here are my favorite Blue Jays vs. Mariners player props and MLB picks for October 19.
Make sure to also check out our full Mariners vs. Blue Jays picks and predictions before first pitch!
Mariners vs Blue Jays Game 6 props
| Player |  |
|---|---|
 Trey Yesavage Over 4.5 strikeouts |
-145 |
 Julio Rodriguez anytime home run |
+450 |
| Vladimir Guerrero Jr. Over 1.5 total bases |
-110 |
Mariners vs Blue Jays player prop picks
Prop #1: Trey Yesavage Over 4.5 strikeouts
I backed this prop the first time Toronto Blue Jays starter Trey Yesavage took the mound in the series, and it didn't go well. His command was erratic, and he clearly labored through moments that felt a little too big for him. Still, the rookie finished with four strikeouts, which showed that even in a rocky outing, his stuff can miss bats.
Now, in an elimination game, the pressure remains high, but that first experience should give Yesavage a meaningful edge. It's also a strong matchup. We've talked plenty about the effects of west-to-east travel on strikeouts and how the Seattle Mariners lineup, despite improving after the deadline, still carries plenty of swing-and-miss.
More importantly, Yesavage's best weapon aligns with Seattle's biggest weakness. His split finger, used about 25% of the time, has produced a whiff rate north of 55 percent, and it's the exact type of pitch this lineup struggles against.
With the stakes high and the line still relatively low, I expect him to lean heavily on it to get the outs he needs. I'd play this prop confidently up to about -160
Prop #2: Julio Rodriguez anytime home run
It's been an impressive postseason for Julio Rodríguez, and there's little reason to believe that momentum slows down now in the biggest game of the series. He opened Game 2 with a home run at Rogers Centre, a park that perfectly suits his swing path and power profile. I think he can do it again here.
While I praised Yesavage's strikeout potential earlier, the flip side is that he's also highly exploitable. Like many young strikeout pitchers, he lives on the edges, and when those swings and misses fade, the damage can pile up quickly. His hard-hit rate sits around 61 percent, a number that would rank near the bottom two percent of the league if he had enough innings to qualify.
That's where Rodríguez comes in. The homer in Game 2? It came off Yesavage himself.
And that wasn't random — it fits perfectly with the types of pitches Yesavage throws and the zones where Rodríguez thrives. Given the matchup, the form he's in, and the price being offered, I'm happy to back Rodríguez to go deep once again.
Prop #3: Vladimir Guerrero Jr. Over 1.5 total bases
No matter how this series ends, Vladimir Guerrero Jr. has silenced nearly every question that once surrounded him. If any doubts remained, they should be gone by now. That's why I have no hesitation backing him to deliver at least one more "moment" in what could be his final game of the season.
As of publication, the Mariners have yet to officially name a starter, but all indications point to Logan Gilbert getting the ball. If that holds true, Guerrero should be eager for the matchup. He has absolutely tormented Gilbert throughout his career, posting an .824 slugging percentage with expected metrics that strongly support those results.
Combine that history with the success Guerrero has already enjoyed in this series against Seattle's pitching staff, and the case becomes straightforward. He's locked in, the matchup is ideal, and the price still offers value. I'd confidently play Guerrero to make an impact at anything better than -130.
How to watch Mariners vs Blue Jays and Game 6 info
| Location | Rogers Centre, Toronto, ON |
| Date | Sunday, October 19, 2025 |
| First pitch | 8:03 p.m. ET |
| TV | FOX |
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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