MLB Home Run Predictions Today: Best HR Prop Bets, Picks, Parlay & Odds for Saturday, September 6

Today's MLB home run props target Freddie Freeman, Nathaniel Lowe, and Trent Grisham.

Quinn Allen - Betting Analyst at Covers.com
Quinn Allen • Betting Analyst
Sep 6, 2025 • 13:05 ET • 4 min read
Freddie Freeman Los Angeles Dodgers MLB
Photo By - Imagn Images. Freddie Freeman rounds the bases after a recent homer.

Another day, another full slate of games in the majors.

Today’s MLB player props analysis will include Trent Grisham, Freddie Freeman, and Nathaniel Lowe. 

Best MLB home run props today

  • TEAM Trent Grisham (+270)
  • TEAM Freddie Freeman (+550)
  • TEAM Nathaniel Lowe (+700)
  • 💲 +19140 parlay💲

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HR Prop #1: Trent Grisham

+270 at DraftKings

Trent Grisham has always had pop in his bat, but I don’t think anyone was predicting him to smack 30 homers this season with the New York Yankees. He’s been their second-best power hitter behind Aaron Judge, and Grisham has gone deep twice in his last four games.

The veteran faces Chris Bassitt today in a crucial matchup with the Toronto Blue Jays. Grisham has enjoyed himself against the righty in the past. He’s 4-for-17 lifetime, and two of those hits have left the yard. 

Grisham has also smacked 24 of his round-trippers against right-handed hurlers, and he’s slugged 12 bombs at home. That short porch in right field is always of help to left-handed hitters like him, too. 

HR Prop #2: Freddie Freeman

+550 at DraftKings

Freddie Freeman may not be putting up massive power numbers, but he’s still gone deep 19 times, and 20 could be on its way tonight. The Los Angeles Dodgers take on the Baltimore Orioles, who send Trevor Rogers to the mound. He’s had success against him, going 3-for-9 with a double and an RBI. 

The former MVP actually just went deep in the series opener on Friday, finishing 2-for-4 in the loss. Freeman also made some noise in August, cracking seven home runs and hitting .310. He’s swinging it well overall.

Freeman has six homers off left-handed pitchers. He’s also left the yard 12 times on the road compared to just seven at Dodger Stadium. Look for Freeman to make it a second straight game with a long ball.

HR Prop #3: Nathaniel Lowe

+700 at DraftKings

The Boston Red Sox went out and acquired Nathaniel Lowe at the deadline to give them some more pop, and they needed another first baseman. He’s actually looked good since coming over from the Nationals, hitting over .300 in September so far and smacking his 18th homer on Tuesday against the Guardians. 

It’s Brandon Pfaadt on the hill tonight a,nd he’s allowed 22 bombs in only 28 starts. Lowe has also raked off him in the past, going 6-for-10 with two doubles and one home run. Pfaadt struggles to keep opponents in the ballpark, and Lowe has done no wrong against the righty. 

Lowe has slugged 16 of his home runs off right-handed pitchers as well.

Today’s HR parlay

Trent Grisham to hit a home run

Freddie Freeman to hit a home run

Nathanial Lowe to hit a home run

Today’s most popular HR bets

  1. Kyle Schwarber, Phillies
  2. Aaron Judge, Yankees
  3. Shohei Ohtani, Dodgers

Betting info courtesy of DraftKings

Odds are correct at the time of publishing and are subject to change.
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Quinn Allen - Covers
Betting Analyst

Quinn Allen is an experienced sports journalist from Vancouver, Canada who fell in love with sports by the time he could walk. He proceeded to play high-level baseball and soccer growing up and eventually played college baseball in the United States.

After his career ended, Quinn received his broadcast journalism degree from BCIT and has since written for many sports publications including ClutchPoints, Gino Hard, and RG, where he plies his trade as a writer and editor.

Quinn's favorite team is Chelsea FC and he'd like to watch a match at Stamford Bridge one day. He loves to bet on NBA player props and encourages others to bet responsibly and not chase losses.

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