The New York Yankees are massive home favorites against the Cleveland Guardians, but I’m not laying a taxed price into this specific contact matchup.
Cam Schlittler has ace-level indicators, but Cleveland’s projected lineup has enough low-strikeout bats to make his best skill less automatic.
Here are my Guardians vs Yankees predictions and MLB picks for Tuesday, June 2.
Who will win Guardians vs Yankees today: Guardians +1.5 (+100)
I see the Cleveland Guardians' moneyline case, but the run line is the better bet.
Cam Schlittler has been excellent, but numbers this sharp are not sustainable forever, and this is the right matchup to test him. His 94th-percentile chase profile meets a Cleveland lineup that rarely expands, and the Guardians own MLB’s second-lowest whiff rate at 22.9%.
The proof of concept is the Tampa Bay Rays, baseball's lowest-whiff team, being the only opponent to tag Schlittler for 3+ earned runs this season.
I’d play Cleveland +1.5 to -115.

Guardians vs Yankees Over/Under pick: Over 7.5 (-105)
It goes without saying that if I expect the Guardians to make Schlitter labor some, then I should like a low total going Over. I do, and I'd play this to 8 at +100.
On the other side of things, like we've hit on often with the New York Yankees, giving them free passes is an issue. Joey Cantillo’s 12.7% walk rate is a problem, as it gives a group with patience and power a chance to create traffic.
For the most part, you're looking for both teams to score three or more runs, and I'm comfortable backing that here.
- ML/RL bets: 25-21, +3.59 units
- Over/Under bets: 29-17, +14.07 units
Guardians vs Yankees odds
- Moneyline: Guardians +200 | Yankees -250
- Run line: Guardians +1.5 | Yankees -1.5
- Over/Under: Over 7.5 | Under 7.5
Guardians vs Yankees trend
The Guardians have hit the F5 Run Line in 28 of their last 40 away games (+15.10 Units / 31% ROI)
How to watch Guardians vs Yankees and game info
| Location | Yankee Stadium, Bronx, NY |
| Date | Tuesday, June 2, 2026 |
| First pitch | 7:05 p.m. ET |
| TV | CleGuardians.TV, YES |
| Guardians starting pitcher | Joey Cantillo (4-2, 3.57 ERA) |
| Yankees starting pitcher | Cam Schlittler (7-2, 1.50 ERA) |
Guardians vs Yankees latest injuries
Guardians vs Yankees weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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