The Arizona Diamondbacks are in the thick of the National League wild-card race, sitting in a tie with the Cincinnati Reds for second place behind the New York Mets.
They have a tough task ahead of them against the Los Angeles Dodgers, who will look to prevent their division rivals from leapfrogging the Reds and the Mets on their way to the postseason.
My Dodgers vs. Diamondbacks predictions break down why Arizona should have some hope tonight, even if L.A.’s ace is looking unhittable at the moment.
Without further ado, let’s hand out some MLB picks for Wednesday, September 24.
Dodgers vs Diamondbacks prediction
Dodgers vs Diamondbacks best bet: Diamondbacks +1.5 (-130)
Well, it seems that for a second straight year, Blake Snell has finally settled back into his groove after a tumultuous start to the season. He’s now struck out 23 batters across his last two starts, spanning 23 innings, and in that time, he’s allowed just two hits and two walks.
The lefty has transformed back into a ground-ball pitcher after spending some time in San Diego and San Francisco, where it makes more sense to pitch the opposite way, and the results have been palpable.
His Expected Slugging is a friendly .328, and while the Expected Batting Average is up to .230, that’s actually an excellent mark relative to a ground-baller.
That’s all due to Snell’s propensity for the swing-and-miss, and with his strikeout rate rising and his troublesome walk rate slowly creeping back down, this is seeming like an impossible pitcher to solve.
The benefit for the Arizona Diamondbacks is that it’s done equally well against lefties and righties – actually striking out less against southpaws – and in the last two weeks, it’s struck out in just 18.4% of plate appearances.
Considering the D-backs are playing with the season on the line and hitting better than almost any team at the moment, made better by their excellent contact numbers, I do think they stand a decent chance against Snell.
I’m a bit less convinced the Los Angeles Dodgers can get to Ryne Nelson, however, considering they’ve forgotten the walk.
That’s how Nelson compounded his occasional issues with the home run, but if L.A. isn’t populating the bases and falls victim to the righty’s improving xBA, this one could be closer in nature than anticipated.
Dodgers vs Diamondbacks same-game parlay (SGP)
We’ll first fortify our stance surrounding Snell in this spot with a very generous line on his earned runs. We’ll just need two, and while he’s worked two straight scoreless outings, he did surrender three runs to this same team just a month ago.
I’m also going to hop aboard the Teoscar Hernandez train again. The slugger now has three hits in his last two games, including a triple and a homer, and is 3-for-5 lifetime off Nelson – something that’s not surprising given his .846 OPS against finesse pitchers and his stronger numbers against fly-ballers. Nelson fits into both categories.
Dodgers vs Diamondbacks SGP
- Diamondbacks +1.5
- Blake Snell Over 2.5 earned runs
- Teoscar Hernandez 2+ total bases
Dodgers vs Diamondbacks odds
- Moneyline: Los Angeles -160 | Arizona +135
- Run line: Los Angeles -1.5 (+105) | Arizona +1.5 (-125)
- Over/Under: Over 8.5 (-115) | Under 8.5 (-105)
Dodgers vs Diamondbacks trend
Los Angeles hit the F5 moneyline in 10 of its last 13 games (+8.45 Units / 34% ROI). Find more MLB betting trends for Dodgers vs. Diamondbacks.
How to watch Dodgers vs Diamondbacks and game info
| Location | Chase Field, Phoenix, AZ |
| Date | Wednesday, September 24, 2025 |
| First pitch | 9:40 p.m. ET |
| TV | SNLA, ARID |
| Dodgers starting pitcher | Blake Snell (5-4, 2.44 ERA) |
| Diamondbacks starting pitcher | Ryne Nelson (7-3, 3.35 ERA) |
Dodgers vs Diamondbacks latest injuries
Dodgers vs Diamondbacks weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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