The Los Angeles Dodgers and Arizona Diamondbacks begin the second game of a three-game series this evening in a pitching mismatch.
LA won last night, and we expect a repeat here.
My Dodgers vs. Diamondbacks predictions and MLB picks break down why I like LA to take care of business on Friday, March 27.
Diamondbacks vs Dodgers predictions
Diamondbacks vs Dodgers best bet: Dodgers -1.5 (-115)
Emmett Sheehan's 2025 campaign was a nice breakout and something I see as sustainable: 30.6% K rate (92nd percentile), 30% whiff rate (93rd). He misses bats, gets plenty of chase, and the Arizona Diamondbacks lineup lacks the contact quality to punish mistakes throughout.
On the other side, Ryne Nelson was a common fade candidate for me last year, and I see no reason for that to change. Especially against this Los Angeles Dodgers lineup. His below-average whiff rate and a hard-hit rate in the bottom 20 percent of baseball loom large against Shohei Ohtani and company.
COVERS INTEL: The Dodgers had four players last season with a double-digit run value against the four-seam fastball. They'll face Ryne Nelson, a pitcher who threw the heater over 60% of the time last season.
Diamondbacks vs Dodgers same-game parlay (SGP)
Sheehan struck out 30% of batters last year, and Arizona's lineup is heavy on free swingers. His slider alone generated a 94th-percentile breaking run value, which is another trouble spot for the Snakes.
I projected his strikeout number at 5.8, so there's plenty of value in the plus-money price as well as the same-game parlay pairing.
Diamondbacks vs Dodgers SGP
- Dodgers -1.5
- Emmet Sheehan Over 5.5 strikeouts
Diamondbacks vs Dodgers home run pick: Will Smith (+400)
Will Smith has some under-the-radar value tonight against Nelson.
His fastball makes up the bulk of his pitching arsenal, which is something you'd think he'd reduce (at least some) against this Dodgers lineup. Enter the slider.
Nelson relied on this pitch throughout 2025 as a go-to secondary option. If he uses that against Smith, he'll be showing him a pitch on which Smith produced the second-highest average exit velocity and hardest hit rate of any Dodger player.
- Best bets: 0-0, 0 units
- SGPs: 0-0, 0 units
- HR picks: 0-0, 0 units
Diamondbacks vs Dodgers odds
- Moneyline: Arizona +265 | Los Angeles -210
- Run line: Arizona +1.5 (+105) | Los Angeles +1.5 (-115)
- Over/Under: Over 8.5 | Under 8.5
Diamondbacks vs Dodgers trend
The Dodgers have won four of the last five head-to-head matchups with the Diamondbacks. Find more MLB betting trends for Diamondbacks vs. Dodgers.
How to watch Diamondbacks vs Dodgers and game info
| Location | Dodger Stadium, Los Angeles, CA |
| Date | Friday, March 27, 2026 |
| First pitch | 10:10 p.m. ET |
| TV | ARID, SportsNet LA |
| Diamondbacks starting pitcher | Ryne Nelson (2025: 7-3, 3.39 ERA) |
| Dodgers starting pitcher | Emmet Sheehan (2025: 6-3, 2.82 ERA) |
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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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