Cubs vs Guardians Prediction, Picks & Odds for Tonight’s MLB Game

Neil Parker - Analyst at Covers.com
Neil Parker • Betting Analyst 16+ years betting experience
Updated: Aug 13, 2024 , 11:16 AM ET • 4 min read

Matthew Boyd still has some catching up to do as he makes his return to the big leagues for the Guardians, and our MLB betting picks will gladly fade him vs. a surging Cubs offense.

Matthew Boyd MLB
Photo By - USA TODAY Sports

The Cleveland Guardians will look for a second consecutive win over the Chicago Cubs at Progressive Field on Tuesday, and the home team will turn to lefty Matthew Boyd for his 2024 season debut following Tommy John surgery last year.

Cleveland and Chicago combined for 17 runs in the series opener, and the Cubbies will send struggling righty Javier Assad to the hill tonight. Our top Cubs vs. Guardians predictions and MLB picks are calling for more offense and Boyd and Assad to have their share of hiccups in the August 13 rematch.

Cubs vs Guardians prediction

My best bet
Matthew Boyd Under 4.5 strikeouts (+120 at FanDuel)

Best odds available in your region

My analysis

Cleveland Guardians starter Matthew Boyd made his last big-league appearance on June 26 of last year, so while his minor-league numbers have been spectacular across five tune-ups, this is still a tall test against a rolling Chicago Cubs offense.

Boyd cruised through six innings on just 63 pitches in his final Triple-A start, so he’s far from fully stretched out, and I’m not expecting him to top 80 pitches on Tuesday. As a result, his window to rack up strikeouts will be partially closed before he even toes the rubber, and Chicago hasn’t been strikeout-happy against southpaws all season.

The Cubs rank 15th with a 22.1 K% against southpaws for the year, and they also have an overall 21% mark in August, which is 10th lowest in the majors. Additionally, Chicago has been more dangerous against lefties all season, and they’re sporting a fourth-ranked .346 wOBA for the month.

Additionally, while Boyd has historically racked up plenty of strikeouts throughout his career with an 8.78 K/9 and 22.7 K% as a starter, he’s never parlayed it into success on the mound. He sports a career 5.02 ERA, 1.33 WHIP, and 4.61 xFIP while allowing a healthy .333 wOBA across his 160 career starts, after all. I’m anticipating his pitch count climbing quickly because of an inability to cruise through the Chicago lineup efficiently tonight.

Finally, I’ve targeted this off-market FanDuel total of 4.5 strikeouts because there has been huge movement to the Under 5.5 at other shops, and I think this is the more accurate number. The Under 5.5 Ks is trading as short as -225 through DraftKings, for example.

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Cubs vs Guardians same-game parlay (SGP)

Matthew Boyd Under 4.5 strikeouts

Over 5.5 F5

Over 8.5

In addition to Boyd making his first start in over a year, Cubs starter Javier Assad has also struggled of late with a 4.88 ERA, 1.75 WHIP, and 6.47 xFIP while also walking more batters than he’s struck out across his past six starts. 

Cleveland is averaging 5.0 runs per game in August, and I’m anticipating the Guardians putting runs on the board against Assad. As noted, Chicago has been packing punch at the dish, and the Cubbies have averaged 5.4 runs per game for the month. 

Both offenses are set up to score early and often again Tuesday.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Cubs vs Guardians odds

Cubs vs Guardians live odds

Cubs vs Guardians opening odds

  • Run line: Chicago +1.5 | Cleveland -1.5
  • Moneyline: Chicago +119 | Cleveland -129
  • Over/Under: Over 8.5 | Under 8.5

Cubs vs Guardians spread and Over/Under analysis

  • There has been a notable move to the Cleveland side of this moneyline, with the opening Guardians -129 steamed all the way to -149 at Pinnacle as of Tuesday morning.
  • As highlighted, Assad hasn’t been sharp, and the Cleveland bullpen ranks first in the majors in both ERA (2.76) and xFIP (3.59).
  • Similarly, there has been movement to the Over at both Pinnacle and bet365.
  • Pinnacle opened with the Over 8.5 trading at -109, and the number has steepened to -118 as of Tuesday morning. There has been a similar five-cent move through bet365.

Cubs vs Guardians trend

The Guardians have hit the Over in 33 of their last 55 games at home (+12.15 Units / 20% ROI). Find more MLB betting trends for Cubs vs. Guardians.

Cubs vs Guardians game info

Location: Progressive Field, Cleveland, OH
Date: Tuesday, 8-13-2024
First pitch: 6:40 p.m. ET
TV: Bally Sports Great Lakes, Marquee Sports Network
Cubs starting pitcher: Javier Assad
(5-3, 3.24 ERA)
Guardians starting pitcher: Matthew Boyd
(0-0, 0.00 ERA)

Cubs vs Guardians latest injuries

Cubs vs Guardians weather

Not intended for use in MA.
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Neil Parker - Covers
Betting Analyst

Neil Parker is, first and foremost, a sports fan. A huge supporter of the Cowboys, Cubs, and Maple Leafs, he has managed to parlay his passion into writing gigs at some of the top websites in the industry.

Neil takes a numbers-based approach to his handicapping and complements his in-depth statistical analysis with a keen eye on the markets to provide the best available odds. He loves to lean on his rolodex of idioms to offset his inner nerd. When it comes to wagering, he throws down on anything that catches his eye at bet365, Betway and BetVictor. He also keeps a close eye on CoolBet because the polar bear brand often has outlier NHL and NFL moneyline prices.

Neil graduated with honors from St. Thomas University in 2007 before completing his BEd at Acadia University in 2010. After teaching a myriad of courses and subjects, he found a groove delivering fun lessons to exceptional learners in non-traditional classroom environments. If his decade-plus teaching run taught him anything about sports betting, it’s to stay the course and use the summer – or offseason – to refresh and prepare to be better in the year to come.

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