Cubs vs Brewers Home Run Picks & Best Bets for NLDS Game 5

Our MLB expert picks are calling for Michael Busch to whack one out of the park in Saturday's winner-take-all NLDS Game 5.

Quinn Allen - Betting Analyst at Covers.com
Quinn Allen • Betting Analyst
Oct 11, 2025 • 09:10 ET • 4 min read
Chicago Cubs Michael Busch MLB
Photo By - Imagn Images. Chicago Cubs first baseman Michael Busch (29) hits a home run.

Game 5 between the Chicago Cubs and Milwaukee Brewers is on the schedule tonight, with a spot in the NLCS on the line.

My MLB player props and home run analysis will highlight two players from this matchup — Michael Busch and William Contreras — on Saturday, October 11.

Cubs vs Brewers home run props

Cubs home run pick

Michael Busch (+330 at Caesars)

Michael Busch was a beast for the Chicago Cubs during the regular season, smacking 38 home runs. He’s carried that power into the playoffs, hitting .292 with four long balls. The slugger has gone deep in three of four games so far in this series, and I’m eyeing him to make that a fourth in the NLDS. 

It’s still unknown who the Milwaukee Brewers will start in Game 5, but to be honest, it doesn’t matter when Busch is this hot. He just homered in back-to-back games in the series to help Chicago climb out of a 0-2 hole. 

I expect Busch to make some noise again. 

Brewers home run pick

William Contreras (+500 at Caesars)

William Contreras is also swinging it well in the postseason, batting .313 with a home run. He went deep 17 times in 2025, and he’s always a threat to do so.

Game 2 saw the catcher leave the yard when the Brew Crew initially took a 2-0 series lead. 

There’s a good chance that the Cubbies send Shota Imanaga to the hill tonight. Contreras has a nice track record against him, going 5-for-12 with three home runs. 

Contreras also cracked nine round-trippers at home this season. 

How to watch Cubs vs Brewers and Game 5 info

Location American Family Field, Milwaukee, WI
Date Saturday, October 11, 2025
First pitch 8:08 p.m. ET
TV TBS

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Quinn Allen - Covers
Betting Analyst

Quinn Allen is an experienced sports journalist from Vancouver, Canada who fell in love with sports by the time he could walk. He proceeded to play high-level baseball and soccer growing up and eventually played college baseball in the United States.

After his career ended, Quinn received his broadcast journalism degree from BCIT and has since written for many sports publications including ClutchPoints, Gino Hard, and RG, where he plies his trade as a writer and editor.

Quinn's favorite team is Chelsea FC and he'd like to watch a match at Stamford Bridge one day. He loves to bet on NBA player props and encourages others to bet responsibly and not chase losses.

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