Brewers vs Mariners Prediction, Picks & Odds — Tuesday, July 22

Jacob Misiorowski has hit the ground running in his MLB career and goes toe to toe with Mariners ace Logan Gilbert tonight. T-Mobile Field is a pitcher's heaven already, but with this caliber of competition, don't expect many runs.

Tony Sartori - Contributor at Covers.com
Tony Sartori • Betting Analyst
Jul 22, 2025 • 09:36 ET • 4 min read

MLB

Match starts: 4 hrs
SEA
31 %
MIL
69 %
EXPERT PICK - TOTAL
u7.0 (-125)
Read Analysis
Jacob Misiorowski Milwaukee Brewers MLB
Photo By - Imagn Images. Brewers rookie Jacob Misiorowski throwing a pitch during the 2025 MLB All-Star Game.

The Seattle Mariners host the Milwaukee Brewers in the second matchup of this three-game series at T-Mobile Park.

My Brewers vs. Mariners predictions target the Under with Jacob Misiorowski squaring off against Logan Gilbert.

Read on for my MLB picks for Tuesday, July 22.

Brewers vs Mariners prediction

My Brewers vs Mariners best bet: Under 7 (-125 at Caesars)

Milwaukee Brewers right-hander Jacob Misiorowski's emergence has been one of the National League's biggest stories, and he gets the ball tonight with a firm lead in the NL Rookie of the Year odds race.

He’s been stellar in his debut season, posting a 4-1 record with a 2.81 ERA and 0.90 WHIP through his first five starts.

His underlying metrics are even stronger, as he boasts a 2.61 expected ERA (xERA) and a .180 expected batting average (xBA). Misiorowski also ranks in the top half of the league in strikeout rate and barrel rate.

A great pitching duel is in store, as the Seattle Mariners counter with right-hander Logan Gilbert. He's also been tremendous this season, posting a 3.39 ERA and 1.05 WHIP through 12 starts.

Like Misiorowski, Gilbert’s analytics are even stronger than his surface-level stats. Gilbert sports a 3.02 xERA, .214 xBA, and a 35.3% strikeout rate, giving us all the ingredients for the Under

Brewers vs Mariners same-game parlay (SGP)

Under 7

Jacob Misiorowski 7+ strikeouts

Logan Gilbert 8+ strikeouts

There is a strong correlation between the Under cashing and both pitchers going Over their strikeout props. These are two of the best strikeout artists in baseball, with each possessing a strikeout rate of 34% or higher.

Subsequently, Misiorowski has recorded seven or more strikeouts in two of his past three starts, while Gilbert just fanned nine batters in his latest outing.

Brewers vs Mariners odds

Brewers vs Mariners live odds

Brewers vs Mariners opening odds

  • Moneyline: Milwaukee +105 | Seattle -125
  • Run line: Milwaukee +1.5 (-220) | Seattle -1.5 (+180)
  • Over/Under: Over 7 (+105) | Under 7 (-125)

Brewers vs Mariners trend

There have been six or fewer total runs scored in three of Misiorowski’s five starts. Find more MLB betting trends for Brewers vs. Mariners.

How to watch Brewers vs Mariners and game info

Location T-Mobile Park, Seattle, WA
Date Tuesday, 7-22-2025
First pitch 9:40 p.m. ET
TV FDSNWI, RSNW
Brewers starting pitcher Jacob Misiorowski
(4-1, 2.81 ERA)
Mariners starting pitcher Logan Gilbert
(2-3, 3.39 ERA)

Brewers vs Mariners latest injuries

Brewers vs Mariners weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Tony Sartori - Covers.com
Betting Analyst

Tony Sartori has written over 1,000 pieces of sports betting content across multiple different media outlets. He covers the NHL, UFC, PGA, NFL and MLB. Tony started part-time while attending the University of Wisconsin-Madison, where he went on to receive a B.A. in Economics and a certificate in Entrepreneurship in 2022. He continues to work full-time in the sports betting landscape.

Due to the variety of sports he covers, Tony is handicapping every day. If he had one piece of betting advice for a new sports bettor, it would be to strictly enforce bankroll management rules for yourself. If you set aside $10,000 for your betting bankroll, then you should generally only be betting between $100 - $500 per play.

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