Blue Jays vs White Sox Prediction, Odds & Home Run Pick for Today's MLB Game

Mike DiStefano - Contributor at Covers.com
Mike DiStefano • Betting Analyst 14+ years betting experience
Updated: Apr 4, 2026 , 12:23 PM ET • 4 min read

Ernie Clement is one of the few Jays' hitters off to a good start, and he'll clear his total bases prop for the third time in four games.

MLB

Apr 04 • 2:10 PM ET
TOR
66 %
CHW
34 %
EXPERT PICK - PROP
Ernie Clement o1.5  Total Bases (+145) Ernie Clement o1.5 Total Bases (+145)
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Ernie Clement (22) hits a single against the Colorado Rockies.
Photo By - Reuters Connect. Ernie Clement (22) hits a single against the Colorado Rockies.

Ernie Clement is riding a four-game hitting streak, and with a lefty expected to throw some bulk innings for the Chicago White Sox, my Blue Jays vs. White Sox predictions expect that streak to continue. 

Find out more in my free MLB picks for Saturday, April 4.

Blue Jays vs White Sox predictions

Blue Jays vs White Sox best bet: Ernie Clement Over 1.5 total bases (+145)

Ernie Clement is on a shortlist of Toronto Blue Jays hitters seeing the ball well right now, batting .310 with a hit in four straight.

The Jays slugger has also gone Over the 1.5 total bases mark twice in his last three games. 

Grant Taylor has been named the opener for the Chicago White Sox, but lefty Anthony Kay is expected to get the ball afterward for some bulk innings. 

Clement crushes lefties. He led the Jays with a .900 OPS against left-handed pitching last season, and I expect that trend to continue here this afternoon. 

Covers COVERS INTEL: Clement had a .549 slug-rate against lefties last year with  26 extra base hits in just 175 at-bats. 

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Blue Jays vs White Sox same-game parlay (SGP)

George Springer has recorded a hit in four of his last five games, and with Grant Taylor expected to pitch just one inning this afternoon, he’s set to face a weak White Sox bullpen that finished 17th in ERA last year and utilized Seranthony Dominguez on Friday.

For the final leg of the SGP, let’s take Under 0.5 strikeouts for Vladimir Guerrero Jr. The Jays slugger has only struck out twice this season, going 5-2 to the Under on this line.

The Jays' superstar sees the ball extremely well and won't swing at anything he doesn't have to.

Blue Jays vs White Sox SGP

  • Ernie Clement Over 1.5 total bases
  • George Springer Over 0.5 singles
  • Vladimir Guerrero Jr. Under 0.5 strikeouts
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Blue Jays vs White Sox home run pick: Vladimir Guerrero Jr. (+450)

This one will be just a half-unit wager with Toronto’s bats struggling. 

However, I do like Vladimir Guerrero Jr. to break out of his skid. Vladdy doesn’t have an extra-base hit yet this season, but a matchup against a hard-throwing lefty could be the key to turning things around.

Guerrero had a .519 slug rate against southpaws last season.

2026 Transparency record
  • Best bets: 2-4, -1.65 units
  • SGPs: 1-5, -1.5 units
  • HR picks: 1-5, -0.95 units

Blue Jays vs White Sox odds

  • Moneyline: Toronto -145 | Chicago +125
  • Run line: Toronto -1.5 (+115) | Chicago +1.5 (-135)
  • Over/Under: Over 6.5 (-105) | Under 6.5 (-115)

Blue Jays vs White Sox trend

The Toronto Blue Jays have covered the first-five innings run line in 16 of their last 21 games (+11.05 Units / 46% ROI).
Find more MLB betting trends for Blue Jays vs. White Sox.

How to watch Blue Jays vs White Sox and game info

Location Rate Field, Chicago, IL
Date Saturday, April 4, 2026
First pitch 2:10 p.m. ET
TV Sportsnet
Blue Jays starting pitcher Eric Lauer
(1-0, 3.38 ERA)
White Sox starting pitcher Anthony Kay
(0-0, 3.86 ERA)

Blue Jays vs White Sox latest injuries

Blue Jays vs White Sox weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Mike DiStefano - Covers
Betting Analyst

Mike DiStefano joins Covers after a successful five-year stint with TSN. Distefano hosted Leafs Lunch, a Toronto Maple Leafs-centric radio show which featured a daily best bets segment where he found the biggest and best value plays of the night. He was also a weekly staple on TSN's flagship radio/tv show "OverDrive" as a betting analyst during their NFL picks segment #TeamAl-DogForever.

A graduate of Centennial College’s Sports Journalism program, Mike has also contributed to the Canadian Baseball Network, FanSided, and The Hockey News.

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