Blue Jays vs Tigers Prediction, Odds & Home Run Pick for Today's MLB Game

Mike DiStefano - Contributor at Covers.com
Mike DiStefano • Betting Analyst 14+ years betting experience
Updated: May 16, 2026 , 08:37 AM ET • 4 min read

Vladimir Guerrero Jr. will snap his skid at the dish with a single today, per our MLB betting picks.

MLB

Match starts: 3 hrs
TOR
35 %
DET
65 %
EXPERT PICK - PROP
Vladimir Guerrero Jr. o0.5  Total Singles (-130) Vladimir Guerrero Jr. o0.5 Total Singles (-130)
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Vladimir Guerrero Jr. Toronto Blue Jays MLB
Photo By - Reuters Connect. Vladimir Guerrero Jr. of the Toronto Blue Jays

Vladimir Guerrero Jr. is in a slump at the plate, but a matchup against Casey Mize may be just what he needs to buck the trend. 

Read on to see why with my Blue Jays vs. Tigers predictions and MLB picks for Saturday, May 16. 

Blue Jays vs Tigers predictions

Blue Jays vs Tigers best bet: Vladimir Guerrero Jr. Over 0.5 singles (-130)

Despite being mired in a lengthy skid at the plate, Vladimir Guerrero Jr. still ranks in the 96th percentile in xBA, and should see some positive regression soon once he finally gets going. 

Today could be that day, especially with Casey Mize on the mound for the Detroit Tigers.

Guerrero Jr. is 3-for-3 against Mize in his career, with two of the three hits being singles. 

I’m betting his singles market specifically because that’s the sweet spot for value, as 80% of his hits this year have been one-baggers

Covers COVERS INTEL: Guerrero Jr. owns a .345 career average against the Detroit Tigers.

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Blue Jays vs Tigers same-game parlay (SGP)

Yohendrick Pinango continues to rack up the hits game by game. He owns a .350 batting average, while recording a hit in 10 of his 14 career outings. 

Ernie Clement is a contact hitter who’s gone Under his strikeout number in 68% of his outings this season, ranking in the 99th percentile in K-rate. 

Blue Jays vs Tigers SGP

  • Vladimir Guerrero Jr. Over 0.5 singles
  • Yohendrick Pinango Over 0.5 hits
  • Ernie Clement Under 0.5 strikeouts
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Blue Jays vs Tigers home run pick: Kazuma Okamoto (+300)

I’m making this a half-unit wager. 

Mize has kept the ball in the yard this season, and hasn’t given up a home run in four starts. However, if there’s one player who could take him deep today, I’m banking on it being Kazuma Okamoto.

The Jays slugger owns a .391 AVG and a .610 SLG against the four-seam fastball, which is Mize’s most used pitch against right-handed batters.

Okamoto has a team-high 10 home runs this year, while ranking in the 95th percentile in hard hit rate.

2026 Transparency record
  • Best bets: 18-25, -3.60 units
  • SGPs: 8-35, -1.20 units
  • HR picks: 8-35, +5.65 units

Blue Jays vs Tigers odds

  • Moneyline: Toronto +110 | Detroit -130
  • Run line: Toronto +1.5 | Detroit -1.5
  • Over/Under: Over 8.5 | Under 8.5

Blue Jays vs Tigers trend

The Blue Jays have hit the team total Under in 15 of their last 20 away games (+9.35 Units / 39% ROI). Find more MLB betting trends for Blue Jays vs. Tigers.

How to watch Blue Jays vs Tigers and game info

Location Comerica Park, Detroit, MI
Date Saturday, May 16, 2026
First pitch 1:10 p.m. ET
TV DSN, SN
Blue Jays starting pitcher Mason Fluharty
(2-0, 5.40 ERA)
Tigers starting pitcher Casey Mize
(2-2, 2.90 ERA)

Blue Jays vs Tigers latest injuries

Blue Jays vs Tigers weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Mike DiStefano - Covers
Betting Analyst

Mike DiStefano joins Covers after a successful five-year stint with TSN. Distefano hosted Leafs Lunch, a Toronto Maple Leafs-centric radio show which featured a daily best bets segment where he found the biggest and best value plays of the night. He was also a weekly staple on TSN's flagship radio/tv show "OverDrive" as a betting analyst during their NFL picks segment #TeamAl-DogForever.

A graduate of Centennial College’s Sports Journalism program, Mike has also contributed to the Canadian Baseball Network, FanSided, and The Hockey News.

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