Blue Jays vs Tigers Prediction, Odds & Home Run Pick for Today's MLB Game

Mike DiStefano - Contributor at Covers.com
Mike DiStefano • Betting Analyst 14+ years betting experience
Updated: May 15, 2026 , 09:41 AM ET • 4 min read

DiStefanos' Prediction: Expect Trey Yesavage to rack up the strikeouts tonight.

MLB

Match starts: 7 hrs
TOR
67 %
DET
34 %
EXPERT PICK - PROP
Trey Yesavage o5.5  Strikeouts Thrown (-110) Trey Yesavage o5.5 Strikeouts Thrown (-110)
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Trey Yesavage of the Toronto Blue Jays MLB
Photo By - Reuters Connect. Trey Yesavage of the Toronto Blue Jays MLB

Toronto Blue Jays starter Trey Yesavage has baffled batters all season, and I expect the same result against a Detroit Tigers lineup that struggles with the splitter. 

Read on to see why with my Toronto Blue Jays vs Detroit Tigers predictions and MLB picks on Friday, May 15. 

Blue Jays vs Tigers predictions

Blue Jays vs Tigers best bet: Trey Yesavage Over 5.5 strikeouts  (-110)

Toronto Blue Jays starter Trey Yesavage has been incredible in his three starts since making his debut on April 28. 

He owns a 0.68 ERA, allowing just one run in 13.1 innings. The strikeout rate has been impressive too, going Over the number in back-to-back starts, racking up 10.15 K/9 in that stretch with a 36% chase rate

When Yesavage is pairing his fastball with that deadly splitter, he becomes nearly unhittable. 

He has a .176 batting average against this season on his splitter with a 38% whiff on the pitch. 

The splitter is Yesavage's put-away pitch, and it’s one that has troubled the Detroit Tigers' bats all season, posting a 39% strikeout rate and 41% whiff rate.

Covers COVERS INTEL: The Tigers rank in the bottom five in strikeout and whiff rate against the splitter this season.  

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Blue Jays vs Tigers same-game parlay (SGP)

Tigers starter Ty Madden throws a heavy dose of the sinker to right-handed batters. That’s a pitch that Vladimir Guerrero Jr. has hit well this year with a .366 avg. I’ll bank on him bumping the slump in a plus-pitching matchup. 

For the final leg of my SGP I’ll bet on Yohendrick Pinango to go Over 0.5 hits. He’s been red hot with the bat, recording at least one hit in nine of his 13 career outings.

Blue Jays vs Tigers SGP

  • Trey Yesavage Over 5.5 strikeouts
  • Vladimir Guerrero Over 1.5 total bases
  • Yohendrick Pinango Over 0.5 hits 
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Blue Jays vs Tigers home run pick: Kazuma Okamoto (+350)

I’m making this a half-unit wager. 

Madden doesn’t throw hard, averaging just 92.7MPH on his pitches, which ranks in the 23rd percentile. 

His primary pitch to righties is a sinker, four-seamer combo. 

Enter Kazuma Okamoto, who has a team-high 10 home runs this year, while ranking in the 94th percentile in hard-hit rate.

He also owns a .596 xSLG with six homers against those two pitches this season.

Mike DiStefano's 2026 Transparency record
  • Best bets: 17-25, -4.60 units
  • SGPs: 8-34, -0.70 units
  • HR picks: 8-34, +6.15 units

Blue Jays vs Tigers odds

  • Moneyline: Toronto -125 | Detroit +113
  • Run line: Toronto -1.5 (+140) | Detroit +1.5 (-160)
  • Over/Under: Over 8.5 (+105) | Under 8.5 (-125)

Blue Jays vs Tigers trend

The Toronto Blue Jays have hit the Game Total Over in 4 of their last 5 games (+2.90 Units / 53% ROI). Find more MLB betting trends for Blue Jays vs. Tigers.

How to watch Blue Jays vs Tigers and game info

Location Comerica Park, Detroit, MI
Date Friday, May 15, 2026
First pitch 6:45 p.m. ET
TV AppleTV
Blue Jays starting pitcher Trey Yesavage
(1-1, 0.68 ERA)
Tigers starting pitcher Ty Madden
(0-0, 2.45 ERA)

Blue Jays vs Tigers latest injuries

Blue Jays vs Tigers weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Mike DiStefano - Covers
Betting Analyst

Mike DiStefano joins Covers after a successful five-year stint with TSN. Distefano hosted Leafs Lunch, a Toronto Maple Leafs-centric radio show which featured a daily best bets segment where he found the biggest and best value plays of the night. He was also a weekly staple on TSN's flagship radio/tv show "OverDrive" as a betting analyst during their NFL picks segment #TeamAl-DogForever.

A graduate of Centennial College’s Sports Journalism program, Mike has also contributed to the Canadian Baseball Network, FanSided, and The Hockey News.

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