The Toronto Blue Jays and the Los Angeles Angels will continue their four-game set at Angel Stadium of Anaheim on Friday night.
The Blue Jays drew first blood on Thursday, and have now won seven of their last 11 games. With the loss, the Angels have now dropped six of their last nine overall.
Who will come out on top in this one? Find out in our free MLB picks and predictions for Blue Jays vs Angels on Friday, May 27.
Blue Jays vs Angels odds
This odds widget represents the best odds available for each betting market from regulated sportsbooks.
The Blue Jays opened as narrow consensus favorites of -112, and have since taken a bit of action to drift up to -120 at many places. The consensus opening total was 7.5, but Over bettors have driven this line up to 8.0 at the majority of sportsbooks.
Blue Jays vs Angels predictions
Picks made on 5/27/2022 at10:20 a.m. ET.
Click on each pick to jump to the full analysis.
If you're signing up for a new sportsbook for the 2022 MLB season, here are two of the best bonuses* available:
A) New users can bet $20 and get $200 in free bets with Caesars! Sign Up Now
B) New users can get two risk-free bets up to $2,000 at PointsBet! Sign Up Now
*Eligible USA locations only
Blue Jays vs Angels game info
• Location: Angel Stadium, Anaheim, CA
• Date: Friday, May 27, 2022
• First pitch: 9:38 p.m. ET
• TV: Apple TV+
Blue Jays vs Angels betting preview
Alek Manoah (5-1, 1.62 ERA): Manoah has entered the AL Cy Young discussion after posting seven quality starts in his first eight chances. He went eight innings when last seen against the Cincinnati Reds on Saturday, allowing only one earned run. Manoah produced a quality start in his lone prior appearance at Angel Stadium last season (two runs over 6 2-3 innings).
Chase Silseth (1-1, 2.61 ERA): Silseth makes just his third major league start on Friday night, and his first against a team not named the Athletics. He held Oakland to one hit over six shutout frames on May 13 before getting tagged for three runs over 4 1-3 innings on May 20. Silseth was promoted straight from Double-A this season after going 2-0 with a 1.73 ERA and 0.846 WHIP in five starts with the Rocket City Trash Pandas.
Be sure to monitor the gametime conditions with our MLB weather info.
Blue Jays: Nate Pearson SP (Out), Tim Mayza RP (Out), Tayler Saucedo RP (Out).
Angels: David Fletcher SS (Out), Austin Warren RP (Out).
Find our latest MLB injury reports.
Betting trend to know
The Angels are 5-12 in their last 17 home games against teams with winning records. Find more MLB betting trends for Blue Jays vs. Angels
Blue Jays vs Angels picks and predictions
Our side and total predictions are based upon our analysis of the line and total in this game. Our best bet is our favorite pick across all markets.
Alek Manoah should win the battle on the mound, and the Blue Jays should win the war on the scoreboard on Friday night.
Manoah has proven his mettle by pitching at least six innings in seven of his first eight starts this year. He hasn’t even needed more than 95 pitches to accomplish the feat, so he’s been economical as well. Blue Jays manager Charlie Montoyo doesn’t have to worry about his ace feeling overworked, and should feel free to let him pitch as deep into this game as possible.
Angels manager Joe Maddon has no such luxury with relative greenhorn Chase Silseth. The 22-year-old rookie has issued four walks in only 10 1-3 innings of work so far. That lack of command figures to get him in trouble, and get the bullpen cranking early.
Neither team boasts an elite relief corps, as L.A. ranks 19th with a 3.84 ERA, with Toronto right behind in 20th (3.90 ERA). The team that uses the fewest relievers will likely prevail in this one.
The Blue Jays are 6-2 in their last eight games against right-handed starters, and that’s thanks in no small part to superstar slugger Vladimir Guerrero Jr., who’s batting .281 against righties with nine homers and 21 RBI — which includes his solo shot against Shohei Ohtani on Thursday night. By contrast, Guerrero is hitting just .143 with no homers and two RBI against southpaws this season.
Prediction: Blue Jays moneyline (-110 at WynnBET)
The Blue Jays’ lineup has struggled to score all year, while the Angels’ order is trending the wrong way. Under bettors should score here.
Toronto is 24th in runs per game this season (3.73), and 21st in team batting average (.232). Bo Bichette, Matt Chapman, and Lourdes Gurriel Jr. are a combined 44-for-244 (.180) on the road in 2022.
Shohei Ohtani has sat in four of the last five games following a pitching start for the Angels. Even if he suits up, bettors should note that the reigning AL MVP is batting a modest 11-for-49 (.224) over the last two weeks.
Jared Walsh – an All-Star in 2021 – has seen his average drop from .275 to .247 over his last 14 games. Tyler Wade has been an inadequate fill-in at shortstop for David Fletcher, batting .156 in May.
The bullpens could be in for a decent night if the home/road splits are any indication. The Blue Jays own a 3.39 ERA in relief on the road, and the Angels’ relievers have produced a 3.35 ERA at home.
Prediction: Under 8.0 (-110 at Caesars)
There are a multitude of reasons to back the Under on Friday night.
Manoah has been one of the AL’s stingiest starters, and he shouldn’t let up against Los Angeles. He owns a 0.75 ERA and a .103 OBA over two starts at night this year. Meanwhile, Silseth should have a moribund Blue Jays offense on its heels early on, if his initial start against the A’s is any indication.
Though both bullpens have underachieved for the most part this year, Under bettors should enjoy enough late leeway thanks to the starting pitchers.
The Under is 12-5 in the Angels’ last 17 home games with the total set between 7.0 and 8.5, and 9-1-1 in Toronto’s last 11 games as the betting favorite.
Pick: Under 8.0 (-110 at Caesars)