The New York Mets visit the San Diego Padres tonight, and I'm expecting first-inning fireworks at Petco Park.
That matchup will headline my top MLB picks today for the "no run first inning" and "yes run first inning" markets.
Here are my best NRFI predictions and YRFI picks for Saturday, June 6.
Best NRFI/YRFI predictions today
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Mariners at Tigers: NRFI (-115)
The Seattle Mariners hand Bryce Miller the ball today, and he's been dominant over his last two outings, posting a 1.87 xERA while walking just 0.90 hitters per nine innings.
While the Detroit Tigers have been red-hot offensively, Miller's command and impressive 20.8% hard-hit rate across his last 10 innings should keep them at bay in the first.
As for Detroit, they hand Keider Montero the baseball, and he's been incredibly reliable. He owns a perfect 11-0 NRFI/YRFI record in 2026 and has posted a 2.85 FIP and 2.36 xERA across his last two starts.
Those underlying numbers suggest he's well positioned to continue that success against Seattle.
I'll play this pick up to -130.
- Time: 1:10 p.m. ET
- Where to watch: DSN, Mariners.TV
Orioles at Blue Jays: NRFI (-115)
The Baltimore Orioles send Kyle Bradish to the mound in Game 2 of the series, and he's allowed a run in the first inning just once in 12 starts.
Bradish owns a 3.58 xERA across his last 13 innings of work and a hard-hit rate of just 30% during that span. Additionally, 52.5% of the contact against him in his last two outings has been on the ground, suggesting he's doing a good job of keeping hitters from elevating the baseball right now.
Braydon Fisher, meanwhile, will be the opener for the Toronto Blue Jays before they turn it over to the rest of the bullpen. He has a 2.15 FIP at home this season, and Fisher has yet to allow a first-inning run across the three starts he's made.
His 2.95 xERA over the last month only adds appeal here.
I'll play this pick up to -130.
- Time: 3:07 p.m. ET
- Where to watch: MASN, Sportsnet
Mets at Padres: YRFI (-105)
New York Mets SP Nolan McLean has allowed a 42.9% hard-hit rate over his last 27 innings of work, and he owns an alarming 6.30 FIP during that span.
The San Diego Padres have only scored 11 times in the first inning this season, but this is a favorable matchup against a pitcher who has struggled to limit hard contact and owns an 8-4 NRFI/YRFI record.
As for Griffin Canning, he has a 6.79 xERA across his previous two starts while allowing a 53.1% hard-hit rate and 15.6% barrel rate. In other words, Canning is getting absolutely torched lately, and he's also walked 3.69 hitters per nine innings over his last 11 2/3 frames.
Between the consistent hard contact and inability to pound the zone, the Mets could jump on him early.
I'll play this pick up to -140.
- Time: 10:10 p.m. ET
- Where to watch: Padres.TV, SportsNet New York
- NRFI/YRFI picks: 15-30, -4.35 units
What is a NRFI prediction?
NRFI (No Run First Inning) and YRFI (Yes Run First Inning) picks add a thrilling twist to the start of an MLB game. A NRFI pick is a prediction that no runs will be scored in the first inning. You're predicting that the starting pitchers for both teams will get through the first inning without allowing any runs, whether by striking out batters, inducing ground balls, or through solid defensive play.
A YRFI pick is the exact opposite. You're predicting that at least one run will be scored in the first inning. In this case, you’re hoping for an early offensive burst such as a leadoff walk, a timely hit, or even a home run.
NRFI and YRFI picks add excitement to the early part of a game and offer immediate gratification for those looking for a quick resolution.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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