The Astros and Red Sox kick off their playoff push Friday night at Fenway, and with Boston dominating at home and facing a shaky arm, I'm backing the Red Sox to get it done in my Astros vs. Red Sox predictions.
Keep reading for the complete breakdown of tonight’s game in my free MLB picks for Friday, August 1.
Astros vs Red Sox prediction
My Astros vs Red Sox best bet: Red Sox moneyline (+116 at BetRivers)
The Boston Red Sox have been a different team at home, going 34-21 at Fenway Park this year. Outside of Coors Field, Fenway is the best offensive ballpark in the majors, and that has allowed the Red Sox to beat up on opposing pitchers, scoring 5.25 runs per game at home.
Boston will have a great opportunity to add to that number tonight, as they take on Hunter Brown. The Houston Astros starter was having an outstanding year through June before things seemingly went sideways in July.
Over his last five starts, Brown has a 5.54 ERA, going only 26 total innings in those outings while the Astros went 2-3 in those games.
Boston is turning to a traditionally solid starter in Cooper Criswell. Criswell hasn’t been great out of the bullpen so far this year, but he was great as a starter down the stretch in 2024, throwing to a 2.01 ERA in five outings.
Criswell likely won’t go deep into the game, but I expect him to give the Red Sox good innings while Boston’s lineup goes to town again in their home bandbox.
I’m taking the Red Sox to win as an underdog tonight.
Astros vs Red Sox same-game parlay (SGP)
Red Sox moneyline
Over 8
Alex Bregman Over 1.5 total bases
While I like the Red Sox to win behind Criswell, he isn’t likely to go deep into the game, and both teams will get on the board tonight.
That’s why I’m also taking the Over in my SGP. I’ll also back Alex Bregman to go Over his total of 1.5 total bases, something he’s done in five straight games.
Astros vs Red Sox odds
Astros vs Red Sox live odds
Astros vs Red Sox opening odds
- Moneyline: Astros -125 | Red Sox +105
- Run line: Astros -1.5 (+130) | Red Sox +1.5 (-155)
- Over/Under: Over 8 (-110) | Under 8 (-110)
Astros vs Red Sox trend
The Boston Red Sox are 6-4 in their last 10 games. Find more MLB betting trends for Astros vs. Red Sox.
How to watch Astros vs Red Sox and game info
| Location | Fenway Park, Boston, MA |
| Date | Friday, 8-1-2025 |
| First pitch | 7:10 p.m. ET |
| TV | Apple TV+ |
| Astros starting pitcher | Hunter Brown (9-5, 2.54 ERA) |
| Red Sox starting pitcher | TBD (X-X, X.XX ERA) |
Astros vs Red Sox latest injuries
Astros vs Red Sox weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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