Roughriders vs Stampeders Prediction, Picks & Odds for CFL Week 12

Ponnaiya’s prediction: With the luxury of a week of rest, back Calgary at home on Saturday night.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Aug 22, 2025 • 14:11 ET • 4 min read

CFL

Match starts: 26 hrs
CGY
38 %
SSK
62 %
EXPERT PICK - MONEYLINE
Calgary +104 Calgary +104
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Vernon Adams Jr. Calgary Stampeders CFL
Photo By - Imagn Images. Calgary Stampeders quarterback Vernon Adams Jr (3) runs with the ball.

Week 12 in the CFL wraps up on Saturday night with a battle between the Saskatchewan Roughriders and Calgary Stampeders. 

These have been the two best teams in the league, and my Roughriders vs Stampeders predictions are betting on the home side to prevail.

Here are my best free CFL picks for this marquee matchup on August 23.

Roughriders vs Stampeders prediction

My Roughriders vs Stampeders pick: Stampeders moneyline (+100 at BET99)

The Calgary Stampeders defeated the Saskatchewan Roughriders 24-10 when these teams clashed in Regina in Week 6. Calgary passed for 428 yards in that game while adding another 134 yards on the ground. 

I'm expecting a closer contest this time, but I like the Stamps to get the win. Although the Riders have won four in a row and currently look like the best team in the CFL, the Stamps have been just as impressive when healthy. 

Two of their three losses came with quarterback Vernon Adams Jr. injured, while the other was in a game with torrential downpour and extreme wind. They squeaked by Winnipeg in their last contest, but outgained the Bombers by 105 yards and won the turnover battle while committing fewer penalties.

That victory could easily have been more lopsided, and they should be even more motivated this week. They trail the Riders by two games in the standings, and a loss would make it an uphill battle for them to close the gap. 

This should be a battle between two evenly matched teams. That said, the Stamps are fresh off a bye and will have home-field advantage.

I also don't trust Riders kicker Brett Lauther, who has only hit 22 of 33 field goal attempts for an ugly 66.7% success rate. Those are the kind of factors that can swing a close contest. 

Roughriders vs Stampeders same-game parlay (SGP)

Stampeders moneyline

Under 50.5

It's tough to handicap the total in this game. Both teams have highly efficient offenses led by MOP candidate quarterbacks, but they also rank first and second in the league in scoring defense. 

That said, Saskatchewan's defense is red-hot, and these teams combined for just 34 points in the first meeting despite rolling up 975 yards of net offense. Both of these stop units do a great job of preventing big plays, and the offenses are comfortable leaning on their ground games. 

In a game of this magnitude, don't be surprised if these offenses play a bit more conservatively than usual, which should lead to this contest finishing below the total. 

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Roughriders vs Stampeders odds

Roughriders vs Stampeders live odds

Roughriders vs Stampeders opening odds

  • Spread: Saskatchewan -1 (-110) | Calgary +1 (-110)
  • Moneyline: Saskatchewan -115 | Calgary -105
  • Over/Under: Over 52.5 (-110) | Under 52.5 (-110)

Roughriders vs Stampeders trend

The Stampeders are 6-2 SU and ATS in the last eight meetings between these West Division foes.

How to watch Roughriders vs Stampeders and game info

Location McMahon Stadium, Calgary, AB
Date Saturday, August 23, 2025
Kick-off 7:00 p.m. ET
TV TSN

Roughriders vs Stampeders key injuries

Roughriders: Samuel Emilus WR (Out), Shawn Bane Jr. WR (Out), Mario Alford WR/KR (Out), Daniel Johnson OT (Out), Trevon Tate G (Out), Sean McEwan C (Out), CJ Avery LB (Out).
Stampeders: Dominique Rhymes WR (Out), Tevin Jones WR (Out), Reggie Begelton WR (Out), Marquel Lee LB, Adrian Greene DB (Out), Tyler Richardson DB (Out).

Roughriders vs Stampeders weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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