Rams vs 49ers Props & Best Bets for Week 10

Matthew Stafford has been in MVP form this season, and we expect the veteran gunslinger to continue showcasing his arm in the red zone.

Ryan Gilbert - Contributor at Covers.com
Ryan Gilbert • Betting Analyst
Nov 8, 2025 • 19:20 ET • 4 min read
Matthew Stafford Los Angeles Rams NFL
Photo By - Imagn Images. Los Angeles Rams quarterback Matthew Stafford (9) throws a pass.

The Los Angeles Rams take their three-game winning streak into the Bay Area when they face the San Francisco 49ers.

There are plenty of Rams vs. 49ers player props to choose from in this matchup, and I’m targeting a kicking prop along with two familiar faces.

Here are my latest NFL picks for Sunday, November 9. 

Rams vs 49ers props

Player Pick FanDuel
49ers Eddy Pineiro Over 6.5 kicking points -130
49ers Christian McCaffrey  Over 49.5 receiving props -120
Rams Matthew Stafford Over 2.5 passing touchdowns +136

Prop bet #1: Eddy Pineiro Over 6.5 kicking points

-130 at FanDuel

Playing kicker props may not be fun, but they can be plenty profitable. San Francisco 49ers kicker Eddy Pineiro has racked up at least seven points in eight of nine contests this season.

Pineiro started the year with six straight games of at least seven points, including double digits in three of them, then had just one in Houston before bouncing back with 10 last week.

The 49ers have given Pineiro plenty of opportunities this season, and he’s been a perfect 19 for 19 on field goals and 14 for 15 on extra points. He should be good for at least two field goals again this week, along with a touchdown or two.

Prop bet #2: Christian McCaffrey Over 49.5 receiving props

-120 at FanDuel

Christian McCaffrey is pretty much a one-man wrecking ball, and the 49ers are taking advantage of that this season.

The running back boasts 596 rushing yards and 626 receiving yards through nine games. McCaffrey has finished with at least 50 receiving yards in eight of nine games, with the lone outlier being 43 yards against Houston.

McCaffrey recorded 82 yards on eight catches back in Week 5 against the Los Angeles Rams, and he should easily clear 50 yards this time around.

Prop bet #3: Matthew Stafford Over 2.5 passing touchdowns

+136 at FanDuel

Los Angeles leaned heavily on Kyren Williams and the running game in recent years, but Matthew Stafford is back in the spotlight this season.

Stafford already sports 21 touchdown passes in eight games, surpassing his total of 20 in 16 games last year, and that’s largely due to his performance in recent weeks. The 37-year-old has thrown for nine touchdown passes over the last two contests, and at least three in four of his last five starts.

The 49ers have already surrendered three touchdown passes on two occasions, including in Week 5 to Stafford. I’ll take the plus odds for him to do it again.

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Ryan Gilbert - Covers
Betting Analyst

Ryan Gilbert brings the passion and pain of being a Philadelphia sports fan. After graduating from Monmouth University with a finance degree, he now uses his statistical background to find inefficiencies in betting markets. With past stops at NHL.com, NBC Sports, and currently at Covers, Ryan's hot picks blend well with the cold ice of a hockey rink.

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