Commanders vs Falcons Predictions, Picks & Best Bets for NFL Week 4

Jayden Daniels is ruled out, but Marcus Mariota is more than capable of leading Washington, as our expert NFL predictions explain.

Ed Scimia - Contributor at Covers.com
Ed Scimia • Betting Analyst
Sep 26, 2025 • 16:48 ET • 4 min read

NFL

Match starts: 19 hrs
ATL
41 %
WAS
59 %
EXPERT PICK - MONEYLINE
Washington +106 Washington +106
Read Analysis
Marcus Mariota of the Washington Commanders
Photo By - Amber Searls-Imagn Images

The Atlanta Falcons will look to recover from a stunning Week 3 defeat as they host the Washington Commanders in Week 4 action.

Atlanta looked awful in its 30-0 loss to the Carolina Panthers, and even without Jayden Daniels, I’m taking Washington to win outright in my Commanders vs. Falcons predictions.

Let’s dive deeper into the bets I like for this game in my free NFL picks for Sunday, September 28.

Commanders vs Falcons prediction

Commanders vs Falcons Best bet: Commanders moneyline (+106)

The loss of Jayden Daniels – who has been ruled out again in Week 4 as he recovers from a knee sprain – is a blow to the Washington Commanders offense, but far from a fatal one. It helps to have a competent backup quarterback, and that’s what Washington has in Marcus Mariota.

Mariota never got to the level of being an elite quarterback, but he’s always looked reasonably good on the field. For his career, the 31-year-old has completed 63% of his passes and thrown 98 touchdowns against 55 interceptions. He has also run for 19 career rushing touchdowns, including one last week against the Las Vegas Raiders.

I think oddsmakers are being a bit too severe in downgrading Washington. The Commanders put up 41 points against Las Vegas with Mariota in for the full game, more than some starting QBs will lead their teams to at any time this season.

The Atlanta Falcons comes into the game 1-2 and having lost by 30 to one of the worst teams in the league last weekend. It’s asking a lot for the Falcons to put things together quickly enough to beat a talented Washington team that still enjoys veteran leadership behind center. I’m taking the Commanders to win outright.

Commanders vs Falcons same-game parlay

Neither offense is primed for a huge day, though I have a lot more faith in the Commanders even with Mariota at the helm. That’s why I’m taking the Under, but still taking Mariota to hit a modest passing total of Over 204.5 yards – something he already did last week against the Raiders.

Commanders vs Falcons SGP

  • Washington Commanders moneyline
  • Under 43.5
  • Marcus Mariota Over 204.5 passing yards

Our big-ticket SGP: Mariota Matters!

Let’s double down on a solid performance out of Mariota, who is more than capable of putting up the numbers required to bring home this parlay.

Commanders vs Falcons SGP

  • Washington Commanders moneyline
  • Under 43.5
  • Marcus Mariota Over 204.5
  • Marcus Mariota Over 1.5 passing touchdowns

Commanders vs Falcons odds

  • Spread: Commanders -3 (-115) | Falcons +3 (-105)
  • Moneyline: Commanders -160 | Falcons +135
  • Over/Under: Over 45.5 (-110) | Under 45.5 (-110)

More NFL picks and odds from Covers


Commanders vs Falcons trend to know

Washington is 4-0 straight up in its last four games against Atlanta. Find more NFL betting trends for Commanders vs. Falcons.

How to watch Commanders vs Falcons

Location Mercedes-Benz Stadium, Atlanta, GA
Date Sunday, September 21, 2025
Kickoff 1:00 p.m. ET
TV CBS

Commanders vs Falcons latest injuries

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Ed Scimia - Covers.com
Betting Analyst

Ed Scimia has been writing about the gaming industry for over 15 years. He graduated from Syracuse University with degrees in Magazine Journalism and Political Science in 2003, and has covered major gambling events like the World Series of Poker in his career. Since joining Covers in 2022, Ed has offered his sports betting analysis primarily on MLB, NFL, college football, and college basketball games, but is willing to take on any sport.

His betting strategy focuses more on finding line value based on deviations from the market rather than traditional handicapping, primarily shopping between DraftKings, FanDuel, and Fanatics in his home state of Connecticut, though he’s not afraid to do deep game analysis to find profitable bets at any book.

Outside of gambling, Ed is an avid curler who competes in mixed doubles on the World Curling Tour and runs a popular curling YouTube channel, Chess on Ice. That experience has come in handy during the Olympics, when he has proven to be a successful curling bettor as well. 

Ed's advice to new bettors is to always open multiple sportsbook accounts and check the odds at each before placing any bet. Successful sports betting is about consistently beating the closing line value, which requires finding spots where one book is offering odds far better than the rest of the market and jumping on those opportunities.

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