Commanders vs Falcons Predictions, Picks & Best Bets for Today's NFL Week 4 Game

Scimia's prediction: Jayden Daniels may be out, but Washington can still win with Marcus Mariota under center.

Ed Scimia - Contributor at Covers.com
Ed Scimia • Betting Analyst
Sep 28, 2025 • 10:47 ET • 4 min read

NFL

Match starts: 1 hrs
ATL
43 %
WAS
57 %
EXPERT PICK - MONEYLINE
Washington +106 Washington +106
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Promo image for Commanders vs. Falcons, including Jayden Daniels and Michael Penix Jr.
Photo By - Imagn Images. Promo image for Commanders vs. Falcons, including Jayden Daniels and Michael Penix Jr.

After a stunning Week 3 setback, the Atlanta Falcons return home to face the Washington Commanders in Week 4.

Coming off an embarrassing 30-0 defeat to the Panthers, Atlanta inspires little confidence — which is why I’m siding with Washington in my Commanders vs. Falcons predictions and NFL picks, even without Jayden Daniels.

Commanders vs Falcons prediction

Commanders vs Falcons Best bet: Commanders moneyline (+106)

The loss of Jayden Daniels — who has been ruled out again in Week 4 as he recovers from a knee sprain — is a blow to this Washington Commanders offense, but far from a fatal one. It helps to have a competent backup quarterback, and that’s what Washington has in Marcus Mariota.

Mariota never got to the level of being an elite quarterback, but he’s always looked reasonably good on the field. For his career, the 31-year-old has completed 63% of his passes and thrown 98 touchdowns against 55 interceptions. He has also run for 19 career rushing touchdowns, including one last week against the Las Vegas Raiders.

I think oddsmakers are being a bit too severe in downgrading Washington. The Commanders put up 41 points against Las Vegas with Mariota in for the full game, more than some starting QBs will lead their teams to at any time this season.

The Atlanta Falcons come into the game 1-2 and have lost by 30 to one of the worst teams in the league last weekend. It’s asking a lot for the Falcons to put things together quickly enough to beat a talented Washington team that still enjoys veteran leadership behind center. I’m taking the Commanders to win outright.

Commanders vs Falcons same-game parlay

Neither offense is primed for a huge day, though I have a lot more faith in the Commanders even with Mariota at the helm. That’s why I’m taking the Under, but still taking Mariota to hit a modest passing total of Over 204.5 yards – something he already did last week against the Raiders.

Commanders vs Falcons SGP

  • Commanders moneyline
  • Under 43.5
  • Marcus Mariota Over 204.5 passing yards

Our big-ticket SGP: Mariota matters!

Let’s double down on a solid performance out of Mariota, who is more than capable of putting up the numbers required to bring home this parlay.

Commanders vs Falcons SGP

  • Commanders moneyline
  • Under 43.5
  • Marcus Mariota Over 204.5 passing yards
  • Marcus Mariota Over 1.5 passing touchdowns

Commanders vs Falcons game predictions

Commanders vs Falcons moneyline prediction

Even without Jayden Daniels, Washington should beat an Atlanta team reeling after last week’s loss to the Panthers.

Commanders vs Falcons spread prediction

The Commanders have too much talent to be getting points in this game. I’d recommend buying a point to get +3.5 if you really want to play the spread, however.

Commanders vs Falcons Over/Under prediction

Make no mistake, Washington will be less explosive without Daniels — it’s just that the Falcons will do even less when they have the ball.

Commanders vs Falcons odds

  • Spread: Commanders -3 | Falcons +3
  • Moneyline: Commanders -160 | Falcons +135
  • Over/Under: Over 45.5 | Under 45.5 

More NFL picks and odds from Covers


Commanders vs Falcons trend to know

The Commanders are 4-0 straight up in their last four games against the Falcons. Find more NFL betting trends for Commanders vs. Falcons.

How to watch Commanders vs Falcons

Location Mercedes-Benz Stadium, Atlanta, GA
Date Sunday, September 21, 2025
Kickoff 1:00 p.m. ET
TV CBS

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Ed Scimia - Covers.com
Betting Analyst

Ed Scimia has been writing about the gaming industry for over 15 years. He graduated from Syracuse University with degrees in Magazine Journalism and Political Science in 2003, and has covered major gambling events like the World Series of Poker in his career. Since joining Covers in 2022, Ed has offered his sports betting analysis primarily on MLB, NFL, college football, and college basketball games, but is willing to take on any sport.

His betting strategy focuses more on finding line value based on deviations from the market rather than traditional handicapping, primarily shopping between DraftKings, FanDuel, and Fanatics in his home state of Connecticut, though he’s not afraid to do deep game analysis to find profitable bets at any book.

Outside of gambling, Ed is an avid curler who competes in mixed doubles on the World Curling Tour and runs a popular curling YouTube channel, Chess on Ice. That experience has come in handy during the Olympics, when he has proven to be a successful curling bettor as well. 

Ed's advice to new bettors is to always open multiple sportsbook accounts and check the odds at each before placing any bet. Successful sports betting is about consistently beating the closing line value, which requires finding spots where one book is offering odds far better than the rest of the market and jumping on those opportunities.

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