Despite finishing with the No. 1 seed in the AFC, the Denver Broncos’ playoff run could be an abrupt one as Josh Allen and the Buffalo Bills come to town today.
With a trip to the AFC Championship on the line, here are our expert Bills vs. Broncos predictions ahead of kickoff on Saturday, January 17.
Bills vs Broncos predictions
- Bills moneyline (+100 at FanDuel)
- Under 46.5 (-118 at FanDuel)
- Allen anytime TD (-110 at FanDuel)
- Franklin Over 19.5 receiving yards (-114 at FanDuel)
Bills vs Broncos best bets
Bills moneyline
While it won't be pretty, Rohit Ponnaiya expects Josh Allen to ultimately carry Buffalo past Denver, with the Bills cashing at +100 in Mile High City.
"With Denver's inept ground game unable to take advantage of Buffalo's soft run D, Josh Allen should will his team to victory."
Under 46.5
Rohit also forecasts a low-scoring affair at Empower Field, with both defenses setting the tone in the high altitude.
"Since losing RB J.K. Dobbins to an injury in Week 10, Denver ranks 25th in rush EPA with R.J. Harvey churning out just 3.4 yards per carry. Bo Nix will have an even tougher time throwing against a Bills defense that holds foes to 159.6 passing yards per game and 5.8 ypa.
Buffalo's ability to throw downfield will also be limited due to a bevy of injuries at WR, and Denver has an elite stop unit. The Broncos lead the NFL in defensive dropback success rate while ranking second in defensive rush success rate."
Bills vs Broncos TD picks
Josh Allen anytime touchdown
Jason Ence is bullish on the reigning MVP finding paydirt for a third straight contest.
"James Cook was held to 46 yards on 15 carries by Jacksonville’s elite run defense, and a similar script could unfold against the Denver Broncos. When the Bills get near the goal line, Allen remains their most dangerous weapon.
Allen has rushed for two touchdowns in each of his last two full games, and I love the -110 price for him to find the end zone again."
Bills vs Broncos props
Troy Franklin Over 19.5 receiving yards
Neil Parker is bullish on Broncos WR2 Troy Franklin eclipsing a modest receiving total, as the second-year Bronco trailed only Courtland Sutton in rec yards during the regular season.
"This is the lowest receiving yards total since Week 1 of the season for Denver Broncos wide receiver Troy Franklin, and he’s recorded 19 or more receiving yards in 13 of 17 games, including eight of nine at home."
Bills vs Broncos odds
Bills vs Broncos game info
| Location: | Empower Field at Mile High, Denver, CO |
| Date: | Saturday, January 17, 2026 |
| Kickoff: | 4:30 p.m. ET |
| TV: | CBS |
Bills vs Broncos latest injuries
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