The Western Michigan Broncos are rolling through the MAC, and they’ll hope to keep the good vibes going when they visit the Eastern Michigan Eagles in Tuesday night MACtion.
The Eagles' rushing defense is the worst in the nation, and my Western Michigan vs. Eastern Michigan predictions expect the Broncos to run roughshod over them.
Read on for my college football picks for Tuesday, November 25.
Western Michigan vs Eastern Michigan prediction
Western Michigan vs Eastern Michigan best bet: Western Michigan -6.5 (-108)
The Western Michigan Broncos were built to exploit the Eastern Michigan Eagles' biggest weakness: EMU can’t stop the rushing game.
EMU allows a nation's worst 225.9 rushing yards per game and now hosts a WMU offense that scampers for the 40th most nationally and leans heavily on dual-threat quarterback Broc Lowry and running back Jalen Buckley.
Western Michigan is 17th in time of possession, and that’s a problem for an Eastern Michigan team that ranks 130th in third-down defense and struggles to sustain drives.
WMU’s Top-15 defense, which limits passing efficiency and explosive plays, further tilts the advantage toward the Broncos.
Western Michigan has covered the spread in five of its previous seven games, and everything points to the Broncos covering against the Eagles.
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Western Michigan vs Eastern Michigan same-game parlay
If Western Michigan has a soft spot, it’s the 4.1 yards per carry the Broncos allow on the ground. Dontae McMillan has topped 73+ yards in three of his last five outings and is fully capable of a big rushing night.
Offensively, the Broncos lean heavily on Lowry’s legs. He’s rushed for 85 or more yards in four of his last six games and now draws a matchup with the worst rushing defense in the nation.
Western Michigan vs Eastern Michigan SGP
- Western Michigan -6.5
- Dontae McMillan Over 72.5 rushing yards
- Broc Lowry Over 84.5 rushing yards
Our deep-ball SGP: Buckley works
WMU running back Jalen Buckley has scored at least one touchdown in three straight games and meets an EMU defense that’s allowed 25 rushing touchdowns this season.
Western Michigan vs Eastern Michigan SGP
- Western Michigan -6.5
- Dontae McMillan Over 72.5 rushing yards
- Broc Lowry Over 84.5 rushing yards
- Jalen Buckley anytime touchdown
Western Michigan vs Eastern Michigan odds
- Spread: Western Michigan -6.5 (-108) | Eastern Michigan +6.5 (-112)
- Moneyline: Western Michigan -225 | Eastern Michigan +188
- Over/Under: Over 45.5 (-110) | Under 45.5 (-110)
Western Michigan vs Eastern Michigan trend to know
Western Michigan has covered the spread in five of its previous seven games. Find more college football betting trends for Western Michigan vs Eastern Michigan.
How to watch Western Michigan vs Eastern Michigan
| Location | Rynearson Stadium, Ypsilanti, MI |
| Date | Tuesday, November 25, 2025 |
| Kickoff | 7:30 p.m. ET |
| TV | ESPN2 |
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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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