Kansas State vs Arizona Prediction, Picks & Odds for September 12 — College Football Week 3

Quincy Craig will have no trouble finding the end zone against a struggling Kansas State side.

Andrew Caley - Senior Betting Analyst at Covers.com
Andrew Caley • Senior Betting Analyst
Sep 11, 2025 • 10:52 ET • 4 min read

NCAAF

Match starts: 23 hrs
HOU
69 %
COLO
31 %
Read Analysis
running back Quincy Craig (24) runs through an opening during the second quarter against the Hawaii Rainbow Warriors at Arizona Stadium.
Photo By - Imagn Images. running back Quincy Craig (24) runs through an opening during the second quarter against the Hawaii Rainbow Warriors at Arizona Stadium.

The start of the 2025 season has been a disaster for the once-ranked 1-2 Kansas State Wildcats, who barely squeaked out a win as 27.5-point faves against North Dakota...

K-State is now just a 1.5-point road favorite against the Arizona Wildcats, and my Kansas State vs. Arizona predictions break down if this is rock bottom for Kansas State, or will AZ help it find a new low?

Check out my college football picks for this Big 12 showdown taking place on September 12, with kickoff at 9:30 p.m. ET on FOX.

Kansas State vs Arizona prediction

Kansas State vs Arizona best bet: Quincy Craig anytime touchdown (+130)

The Kansas State Wildcats are down bad. They enter this week’s matchup against the Arizona Wildcats, lucky to be 1-2, and are 0-3 against the spread.

QB Avery Johnson has been fine, but he still misses too many throws, while only rushing for 78 yards and one touchdown.

What may be more shocking is the K-State defensive front has been pushed around this season. It allowed Army to possess the ball for more than 40 minutes, and the Wildcats had the ball for less than four minutes in the second half.

Now, they’ll head on the road on a short week to take on another Wildcats team feeling pretty good about itself. Arizona is 2-0 coming off a 48-3 win over FCS Weber State following a 40-3 win over Hawaii.

Senior QB Noah Fifita is back under center and had a great game against Weber State, but it was the run game that was the star against Hawaii. 

Portland State transfer RB Quincy Craig has looked like the most dynamic back for Arizona this season, rushing for 156 yards and a score on 15 carries. He also got the early work in both games, and will be called upon in the red zone on Friday. 

Kansas State vs Arizona same-game parlay

While Arizona has yet to give up a touchdown this season, playing Hawaii and FCS Weber State largely accounts for that. Despite its struggles, Kansas State is still a talented football team.

I think Arizona’s defense — which returns nine starters — will be improved this season, but Kansas State cannot afford another letdown.

Avery Johnson rushed the ball just three times in the loss to Army. It feels like there is no way Chris Klieman’s staff will let that happen again. I’ll take Johnson Over 39.5 rushing yards vs. an Arizona team he went for 110 rushing yards against last season.

With that in mind, if Johnson can kickstart the K-State offense, I’m betting we see some scoring on Friday night.

Kansas State vs Arizona SGP

  • Quincy Craig anytime touchdown
  • Avery Johnson Over 39.5 rushing yards
  • Over 54.5 (+503)

Our deep-ball SGP: TDs galore

  • Let's turn an anytime TD for Craig into 2+ TDs, as he should get more work in what should be Arizona's first competitive game.
  • Let's add an Avery Johnson anytime TD as well, since the QB rushed for seven TDs last season.

Kansas State vs Arizona SGP

  • Quincy Craig 2+ touchdowns
  • Avery Johnson Over 39.5 rushing yards
  • Avery Johnson anytime touchdown
  • Over 54.5

Kansas State vs Arizona odds

  • Spread: Kansas State -1.5 | Arizona +1.5
  • Moneyline: Kansas State -120 | Arizona +100
  • Over/Under: Over 54.5 | Under 54.5

Kansas State vs Arizona trend to know

Kansas State has only covered the spread in four of their last 14 games for -6.95 Units and a -45% ROI. Find more college football betting trends for Kansas State vs Arizona.

How to watch Kansas State vs Arizona

Location Arizona Stadium, Tucson, AZ
Date Friday, September 12, 2025
Kickoff 9:30 p.m. ET
TV FOX

Kansas State vs Arizona latest injuries

Kansas State vs Arizona weather

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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Andrew Caley
Senior Betting Analyst

When his dreams of becoming the next Steve Nash died, all Andrew "Taco" Caley wanted to do was write about sports, something he's been doing at Covers for more than a decade. A Journalism School grad from Holland College in Charlottetown, PEI, Andrew previously worked at The Chronicle Herald and Star Metro, but knew in his heart that his future lay in sports. He began at Covers as a news editor and has now done everything under the sun when it comes to content. His work has been seen on TSN, Sportsnet, VSiN, and CBS. These days Andrew's betting expertise is focused on his favorite teams; the Toronto Blue Jays and Toronto Raptors. He's also an avid college football fan and bettor. He can't be friends with you if you don't appreciate a Service Academy Under. The sportsbook where he does the bulk of his betting is bet365 thanks to its numerous prop betting options and competitive odds. His best advice? Find the balance between the numbers and what you see on the playing field. Then find the best price using multiple books. And don’t ask him where the nickname Taco comes from. It's not an interesting story. Seriously.

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