Villanova vs St. John's Prediction, Picks & Odds for Tonight's College Basketball Game

Krest's Prediction: Look for a comfortable bounce-back victory over Villanova!

Shawn Krest - Betting Analyst at Covers.com
Shawn Krest • Betting Analyst
Feb 28, 2026 • 09:26 ET • 4 min read

NCAAB

Match starts: 8 hrs
VILL
50 %
SJU
50 %
EXPERT PICK - SPREAD
St. John's -7.5 (-116) St. John's -7.5 (-116)
Read Analysis
Zuby Ejiofor of the St. John's Red Storm CBB
Photo By - Reuters Connect. Zuby Ejiofor of the St. John's Red Storm CBB

If there was ever a game to throw out the film and move on, the St. John's Red Storm played it earlier this week.

The Red Storm scored 40 points in a 32-point loss at UConn and missed their last 24 shots over the final 17:42.

The Villanova Wildcats are not UConn, and St. John's will return to form as the team that had a 13-game win streak heading into that contest.

My Villanova vs. St. John's predictions and college basketball picks call for the Johnnies to get a cover at home.

Villanova vs St. John's prediction

Villanova vs St. John's best bet: St. John's -7.5 (-110)

The Villanova Wildcats' defense isn't on UConn's level. The Huskies are top-10 against 2-point shots and top 20 against the three. Nova ranks No. 150 in the nation against both, and their last five opponents shot .567 from two.

The St. John's Red Storm got good shots against UConn. Nine of the 24 straight misses were within 10 feet. At home, against a softer foe, those shots will fall.

The Red Storm had been playing with their food, failing to cover two of the last three as 7.5-point or greater favorites. The UConn debacle will be a wake-up call.

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Villanova vs St. John's same-game parlay

Villanova plays at the No. 327 pace in the country, but the Wildcats have sped things up, making the Over a solid play. 

Zuby Ejiofor was the last St. John's player to make a basket. He'll be the reason the Johnnie's cover the number tonight. 

Villanova vs St. John's SGP

  • St. John's -7.5
  • Over 146.5 points
  • Zuby Ejiofor Over 15.5 points

Our beyond the arc SGP: Tough Night!

Acaden Lewis scored just three points and shot 1-for-7 in the first game against St. John's. Against Quad 1 foes this season, he's averaging 8.1 points and hitting just .300 from the field, compared to 14.5 and .526 against everyone else.

Bryce Lindsay has made 0 or 1 three-pointers in four of the last six games. The odds seem out of line here, and we'll take advantage. 

Villanova vs St. John's SGP

  • St. John's -7.5
  • Zuby Ejiofor Over 15.5 points
  • Acaden Lewis Under 12.5 points
  • Bryce Lindsay Under 1.5 made threes

Villanova vs St. John's odds

  • Spread: Villanova +7.5 (-110) | St. John's -7.5 (-110)
  • Moneyline: Villanova +245 | St. John's -300
  • Over/Under: Over 145 (-110) | Under 145 (-110)

Villanova vs St. John's betting trend to know

Villanova has hit the Game Total Over in 12 of their last 15 games. Find more college basketball betting trends for Villanova vs. St. John's.

How to watch Villanova vs St. John's

Location Madison Square Garden, New York, NY
Date Saturday, February 28, 2026
Tip-off 8:00 p.m. ET
TV FOX

Villanova vs St. John's key injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Shawn Krest
Betting Analyst

Since quitting his job as bank assistant vice-president in 2000, Shawn has covered Final Fours, Super Bowls, World Series games and title fights in boxing and UFC. His work has appeared on ESPN, MLB.com, Sports Illustrated and dozens of other outlets. His book, Baseball Meat Market was published in 2018. He lives in North Carolina with his dog Toby, eight turtles, and wife.

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