Victor Wembanyama and the San Antonio Spurs visit the Memphis Grizzlies tonight at the FedExForum, with tip-off scheduled for 8 p.m. ET.
Second-year guard Stephon Castle has been in his bag, and my Spurs vs Grizzlies predictions expect him to show out.
Read more in my NBA picks for Wednesday, March 25.
Spurs vs Grizzlies prediction
Spurs vs Grizzlies best bet: Stephon Castle Over 17.5 points (+100)
While Victor Wembanyama gets a ton of credit for the San Antonio Spurs’ success, other pieces have also been key to their rise to the second-best team in the Western Conference.
Stephon Castle is a perfect example.
The 21-year-old is averaging 16.5 points per game, cashing the Over in points in five of his last seven contests.
Castle has hit the Over in two of his last three road outings, also scoring 23 last week against the Los Angeles Clippers. The Memphis Grizzlies are an easier matchup for shooting guards, allowing 22.8 ppg to the position.
Also, Castle’s backcourt mate, De’Aaron Fox, won’t play in Memphis due to back soreness. That means the young guard will have a heavier workload for the Spurs.
In nine games without Fox, Castle has averaged 18.9 points.
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Spurs vs Grizzlies same-game parlay
Wemby just dropped 26 against the Heat, and he’s cashed the Over in five of his last nine appearances. The big man is averaging 24.3 ppg overall and 26.6 per outing in March.
Wembanyama already erupted for 30 earlier in the campaign vs. Memphis, and he’ll also benefit from Fox’s absence with more offensive workload.
Dylan Harper is a sparkplug off the bench for the Spurs, and he’s one of their better playmakers. Harper is averaging 3.8 dimes per game, and he just dished out six assists on Monday evening.
The Rutgers product had finished with five dimes in four of five games before Monday, and without Fox — an elite facilitator — he’ll be tasked with stepping up as a passer.
Spurs vs Grizzlies SGP
- Stephon Castle Over 16.5 points
- Victor Wembanyama Over 26.5 points
- Dylan Harper Over 5.5 assists
Our "from downtown" SGP: Spur of the moment
The Spurs are averaging 119.2 ppg this season, which ranks third in the Association. They’ve cashed the Over in three of their last four, and San Antonio just scored 136 against the Heat.
They’ve hit the Over in team points in two of the last four meetings with Memphis, who is 22nd in defensive rating.
Keldon Johnson has cashed the Over in triples in back-to-back contests and in three of his last four appearances. He’s 5-for-9 from downtown across his last two games alone.
Spurs vs Grizzlies SGP
- Victor Wembanyama Over 26.5 points
- Dylan Harper Over 5.5 assists
- Spurs team total Over 124.5
- Keldon Johnson Over 1.5 threes
Spurs vs Grizzlies odds
- Spread: Spurs -16.5 (-115) | Grizzlies +16.5 (-105)
- Moneyline: Spurs -1600 | Grizzlies +900
- Over/Under: Over 232.5 | Under 232.5
Spurs vs Grizzlies betting trend to know
The Spurs have hit the moneyline in 27 of their last 40 away games (+29.25 Units / 32% ROI). Find more NBA betting trends for Spurs vs. Grizzlies.
How to watch Spurs vs Grizzlies
| Location | FedExForum, Memphis, TN |
| Date | Wednesday, March 25, 2026 |
| Tip-off | 8:00 p.m. ET |
| TV | FDSN-SW, FDSN SE-MEM |
Spurs vs Grizzlies latest injuries
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