- UPDATE: Added a +800 SGP + who will win prediction.
The Philadelphia 76ers are down 1-0 to the New York Knicks and now must try to even the series without Joel Embiid.
Forward Kelly Oubre Jr. led the Sixers with five boards in the blowout defeat, and my 76ers vs. Knicks predictions expect him to attack the glass for the undersized Sixers.
Find out more in my NBA picks for May 6.
76ers vs Knicks Game 2 prediction
Who will win 76ers vs Knicks Game 2?
Knicks: The Game 1 result was a perfect storm for Philadelphia. The 76ers were still sweating from a Game 7 in Boston a day prior while the Knicks just couldn’t miss. New York won’t shoot as well in Game 2 but is still in control as long as Joel Embiid is dragging himself around on defense. The Knicks have too many offensive options and this spread says the Knicks take a 2-0 lead to Philly.
76ers vs Knicks best bet: Kelly Oubre Jr. Over 5.5 rebounds (+100)
Kelly Oubre Jr.’s role as a rebounder spikes in this series, and now with Joel Embiid ruled out for Game 2, this prop looks even better.
The New York Knicks’ high-action drags Philly's centers away from the paint on defense, and all of them lack mobility, preventing them from crashing the glass.
Oubre will often be the closest defender to the rim, and he’s active enough to contest for rebounds. He hauled in five boards on eight potential chances in just 27 minutes in Game 1.
So far in the postseason, Oubre is averaging 5.9 rebounds on 10.0 chances. New York’s shooting will regress in Game 2, leaving more rebounding opportunities, and Oubre’s projections sit at 6+ boards.
COVERS INTEL: Before Oubre’s five rebounds in Game 1, the 6-foot-8 forward pulled down seven rebounds in each of his two meetings with the Knicks in the regular season.
76ers vs Knicks Game 2 same-game parlay
The Philadelphia 76ers couldn’t pick up the pace in Game 1. The Knicks’ hot shooting forced them to start too many possessions from the inbounds.
Philadelphia’s best plan of attack is to avoid the half-court defense by fueling fastbreaks and transition. New York won’t shoot as well as it did in the opener, but its offense is a tough solve for Philly.
Karl-Anthony Towns has been more of a playmaker for the Knicks in the playoffs. But with the 76ers missing Embiid, KAT could see smaller checks and more space from the top of the key.
He’ll either attack inside or let it fly from mid-range. Projections are as high as 22 points for Game 2.
76ers vs Knicks SGP
- Over 215
- Kelly Oubre Over 5.5 rebounds
- Karl-Anthony Towns Over 18.5 points
Our "from downtown" SGP: Big man about Towns
Towns has been awesome for New York so far in the postseason, and with Embiid a no-go tonight, KAT has an edge. He’s been a catalyst for playmaking (averaging six assists), and Game 2 projections call for as many as 22 points with a lean toward two triples.
76ers vs Knicks SGP
- Knicks moneyline
- Over 215
- Karl-Anthony Towns Over 18.5 points
- Karl-Anthony Towns Over 4.5 assists
- Karl-Anthony Towns Over 1.5 threes
76ers vs Knicks odds for Game 2
- Spread: 76ers +7 | Knicks -7
- Moneyline: 76ers +225 | Knicks -275
- Over/Under: Over 215 | Under 215
76ers vs Knicks betting trend to know
The Knicks make good on big spreads at home. New York is 24-4 SU and 21-7 ATS (75%) when laying more than five points at Madison Square Garden, including 3-1 SU and ATS so far in the playoffs. Find more NBA betting trends for 76ers vs. Knicks.
How to watch 76ers vs Knicks Game 2
| Location | Madison Square Garden, New York, NY |
| Date | Wednesday, May 6, 2026 |
| Tip-off | 7 p.m. ET |
| TV | ESPN |
76ers vs Knicks latest injuries
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