The San Francisco Giants host the New York Yankees in MLB action today, with first pitch scheduled for 4:35 p.m. ET.
New York took Wednesday's season-opener in a 7-0 blowout, and my Yankees vs. Giants predictions expect the visitors to win again.
Here are my best free MLB picks for March 27.
Yankees vs Giants predictions
Yankees vs Giants best bet: Yankees moneyline (-130)
The San Francisco Giants have a potent lineup featuring Rafael Devers and Willy Adames. That said, they're still not on the same level as the New York Yankees.
The Yankees had the most productive offense in the majors last year, and that lineup returns intact. They'll light up Robbie Ray, who is coming off a solid season but had worrying underlying metrics. Ray was in the Bottom 10th percentile in average exit velocity, and the bottom 20th percentile in hard-hit rate.
Meanwhile, Yankees hurler Cam Schlittler should build on an impressive rookie campaign by mixing in more breaking pitches.

Yankees vs Giants same-game parlay (SGP)
Schlittler fanned 11 batters in 9 2/3 frames during spring training. He averages 98 mph on his four-seamer and sinker, with his cutter now at 94.7 mph — nearly 3 mph higher than last year. He averaged 10.4 K/9 last season and will be even more overpowering in 2026.
Aaron Judge is the best hitter in the world, and over the last two years, he's posted an incredible .457 OBP while plating 259 runs in 310 games.
Not only does Ray give up too much hard contact, but San Fran's bullpen sits near the bottom of the majors in most preseason rankings. This could be a game where the Yankees win by multiple runs, especially if Judge and Schlittler play well.
Yankees vs Giants SGP
- Cam Schlittler Over 4.5 strikeouts
- Aaron Judge Over 0.5 runs
- Yankees -1.5
Yankees vs Giants home run pick: Aaron Judge (+240)
Judge went 0-for-5 with four strikeouts on opening night. That said, the three-time AL MVP is a proven slugger who has mashed more than 50 dingers in three of the last four seasons.
He should bounce back and this is a great matchup for him. Judge has jacked three dingers in four career games at Oracle Park. The towering right-hander also has the platoon advantage against Ray and has gone 3-for-8 with three homers in his career against him.
- Best bets: 1-0, +1 units
- SGPs: 0-1, -1 units
- HR picks: 0-1, -1 units
Yankees vs Giants odds
- Moneyline: Yankees -134 | Giants +114
- Run line: Yankees -1.5 (+122) | Giants +1.5 (-146)
- Over/Under: Over 8.5 (-102) | Under 8.5 (-120)
How to watch Yankees vs Giants and game info
| Location | Oracle Park, San Francisco, CA |
| Date | Friday, March 27, 2026 |
| First pitch | 4:35 p.m. ET |
| TV | YES, NBC Sports Bay Area |
| Yankees starting pitcher | Cam Schlittler (2025: 4-3, 2.96 ERA) |
| Giants starting pitcher | Robbie Ray (2025: 11-8, 3.65 ERA) |
Yankees vs Giants latest injuries
Yankees vs Giants weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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