The Cleveland Guardians are in a healthy rut. They've dropped eight of their last 10 games, including seven straight overall.
Let’s break it all down with my July 4 MLB picks.
Tigers vs Guardians prediction
My Tigers vs Guardians best bet: Jose Ramirez Over 1.5 total bases (+105 at bet365)
Jose Ramirez, like the Cleveland Guardians offense as a whole, has gone cold of late, but a matchup with the Detroit Tigers could be just what the doctor ordered to help him get back on track.
Ramirez has torched his AL Central foes over the past year and change, averaging 2.4 bases per game while clearing in 13 of 22 head-to-head meetings. That’s an impressive 59% hit rate.
While Reese Olson is a quality pitcher, he hasn’t made a major league appearance since the middle of May.
Ramirez has performed far better against right-handed pitchers this season. He’s averaged exactly two bases per game in contests featuring a righty starter compared to 1.4 over 25 games against left-handed starters.
Tigers vs Guardians same-game parlay (SGP)
Jose Ramirez Over 1.5 total bases
Colt Keith Over 1.5 total bases
Over 7.5
Colt Keith has hit the ball very well of late, especially on the road. He’s averaged 2.0 total bases over his last 20 away games. Isolating Slade Cecconi’s three most used pitches, Keith is hitting .387 with a .444 wOBA in road games over the last two months.
The Tigers are red-hot at the plate, and their games have averaged 10.5 combined runs over the last 10. If Ramirez and the Guardians can chip in, this game should feature eight or more.
Tigers vs Guardians odds
Tigers vs Guardians live odds
Tigers vs Guardians opening odds
- Moneyline: Detroit -110 | Cleveland -110
- Run line: Detroit -1.5 (+145) | Cleveland +1.5 (-170)
- Over/Under: Over 8 | Under 8
Tigers vs Guardians trend
Jose Ramirez has averaged 2.7 total bases over his last 10 home games against a right-handed starter. Find more MLB betting trends for Tigers vs. Guardians.
How to watch Tigers vs Guardians and game info
| Location | Progressive Field, Cleveland, OH |
| Date | Friday, 7-4-2025 |
| First pitch | 7:10 p.m. ET |
| TV | FDSN-Detroit, CLEGUARDIANS.tv |
| Tigers starting pitcher | Reese Olson (4-3, 2.96 ERA) |
| Guardians starting pitcher | Slade Cecconi (3-3, 3.64 ERA) |
Tigers vs Guardians latest injuries
Tigers vs Guardians weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
