MLB Spring Training Picks and Predictions for February 22: Ray Wins the Day for Giants

Our MLB betting picks for Sunday afternoon are calling for a San Francisco Giants win vs. the Chicago Cubs, and much more.

Robert Criscola - Betting Analyst at Covers.com
Robert Criscola • Betting Analyst
Feb 22, 2026 • 09:46 ET • 4 min read
San Francisco Giants MLB Robbie Ray
Photo By - Reuters Connect. San Francisco Giants SP Robbie Ray.

It's the first Sunday of the 2026 Spring Training slate, with 16 games on the docket. 

My MLB picks have boiled things down to the best three bets on the board for Sunday, February 22. See why I'm targeting the Giants moneyline at a coin-flip price.

Spring Training predictions for February 22

Picks bet365
Giants Giants moneyline -120
Athletics Athletics moneyline -140
Dodgers Dodgers moneyline -125
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Pick #1: Giants moneyline

-120 at bet365

San Francisco Giants SP Robbie Ray makes his 2026 Spring Training debut, and he had a sparkling exhibition season last year, going 3-0 with a 2.08 ERA over 17 1/3 innings.

Contrast that with Colin Rea, today's Chicago Cubs starter who had a 7.94 ERA last spring in limited opportunities.

Rea took on the Giants twice last year, and the results were not pretty. He authored a 9.31 ERA over 9 2/3 combined frames.

Pick #2: Athletics moneyline

-140 at bet365

Luis Severino had a forgettable campaign overall as the Athletics' ace last year, but his road ERA of 3.02 was nothing to be ashamed of.

The Cleveland Guardians offense was far from scary in 2025, putting up the third-fewest runs per game. 

Sutter Health Park was a hitter's haven last year, but the Athletics offense still traveled well, authoring 4.51 runs per game on the road.

The A's were sixth in the majors in batting average vs. lefties last year, and it's a southpaw on the bump today for Cleveland in Parker Messick.

Pick #3: Dodgers moneyline

-125 at bet365

The Los Angeles Dodgers have owned their rivalry with the San Diego Padres of late, going 66-40 since 2020, with a 12-6 record dating back to the 2024 NLDS. 

The Dodgers had a strong 2025 Spring Training, going 14-9 with a +15 run differential. The Padres, by contrast, went 12-17 with a -33 run differential in Cactus League play last year.

L.A. is trotting out a highly-touted prospect in Jackson Ferris today. His opposite number is Randy Vasquez, a solid but unspectacular rotation piece with a career 4.08 ERA. 

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Robert Criscola - Covers.com
Betting Analyst

Robert M. Criscola’s road to becoming a Covers publishing editor began with an internship at Metro New York, which eventually turned into a freelance job at MetroBet covering many sports from a wagering angle, including horse racing. He continued to focus on “The Sport of Kings” by writing for shapperdacapper.com, danonymousracing.com, and informer.fanxt.com before joining the team at the TwinSpires Edge in 2019 as a regular contributor and weekend editor. “Crisco” began writing game previews for Covers in 2022 and joined the editing team in 2023.

His best advice for sports bettors? Bet with your head, not over it.

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