The Boston Red Sox have caught fire of late, winning nine out of their last 11 games which is a stretch that dates back to their series win over the Los Angeles Dodgers in late July. Now, they’ll look to secure a sweep of the Kansas City Royals at home on Wednesday.
We’ll explain in our Royals vs. Red Sox predictions how Boston should be set up to continue flexing its muscles at the plate while its newly-acquired starter could be in an extended period of trouble.
Without further ado, let’s hand out some MLB picks for Wednesday, August 6.
Royals vs Red Sox prediction
My Royals vs Red Sox best bet: Over 8.5 (-112 at DraftKings)
At this point, it’s hard to say the jury’s still out on late-career Michael Wacha. All the righty has done is pitch to an ERA under 3.40 for a fourth straight season, and he’s continuing to do so by inducing soft contact in the air with few walks against him.
The benefit, of course, is that the Kansas City Royals’ outfield defense is one of the best in baseball, and their park’s large dimensions help keep the ball in the park for Kansas City’s gloves to go to work.
Now, the righty has only grown stronger as the year’s gone on. He posted a season-best .238 Expected Batting Average in July with a slightly elevated .419 Expected Slugging, but the latter has always posed something of a problem for Wacha – which is why pitching at home is always a plus.
The right-hander carries a 4.10 road ERA into this start with a 2.63 ERA at home, and Boston’s small home park may wind up costing this fly-ball maestro on a couple of occasions.
On the other side of the coin, life should really be difficult for Dustin May as a ground-ball pitcher entering one of the worst teams in the league when it comes to defending in the infield.
Boston’s failed to support these types of pitchers for multiple years now as they search for answers all around the diamond, and May will be hoping to start finding more strikeouts to remove the variables that come along with batted balls on the ground.
He's done a slightly better job of that of late, striking out 22 in 21 1/3 innings last month, but he’ll meet a Royals team here which has struck out in just 18.5% of plate appearances while posting a beefy .214 Isolated Power in the last two weeks.
Kansas City ranks an impressive 12th in OPS to ground-ball arms which is seven spots higher than the reverse split, while Boston sits third against fly-ball pitchers.
It’s a dream matchup for both sides, really, and while the Boston Red Sox continue to rake, the Royals have made a sudden resurgence in the last 14 days in ranking 13th in wRC+.
I believe in both lineups here, particularly with Wacha stepping away from the sanctity of his home ballpark and into a tough environment against a team which has done a ton of slugging of late.
Royals vs Red Sox same-game parlay (SGP)
We’ll kick things off here with Alex Bregman, who’s cooled off a bit of late but is just a couple of games removed from a two-hit performance.
He’s done an exceptional job of hitting fly-ball pitchers like Wacha this season, running a .304 average next to a robust .589 slugging percentage, and in his six at-bats versus the righty in his career owns a .386 xBA and .551 xSLG.
I’m also pretty cool on the Red Sox’ ability to work counts in this one, as they carry a measly 7.6% walk rate into this one over the last two weeks.
Wacha is a master of control, and he’s now walked just two batters in his last three starts – extending his stretch of hitting the Under on this prop in 11 of his last 18 outings.
I expect Boston to rip the ball against the righty, but I don’t expect it to sit around and wait at the dish in a matchup like this.
Royals vs Red Sox odds
Royals vs Red Sox live odds
Royals vs Red Sox opening odds
- Moneyline: Kansas City +116 | Boston -134
- Run line: Kansas City +1.5 (-170) | Boston -1.5 (+140)
- Over/Under: Over 9 | Under 9
Royals vs Red Sox trend
The Kansas City Royals have covered the Run Line in 33 of their last 46 away games (+17.30 Units / 25% ROI). Find more MLB betting trends for Royals vs. Red Sox.
How to watch Royals vs Red Sox and game info
Location | Fenway Park, Boston, MA |
Date | Wednesday, August 6, 2025 |
First pitch | 7:10 p.m. ET |
TV | FanDuel Sports Network-Kansas City, NESN |
Royals starting pitcher | Michael Wacha (5-9, 3.38 ERA) |
Red Sox starting pitcher | Dustin May (6-7, 4.85 ERA) |
Royals vs Red Sox latest injuries
Royals vs Red Sox weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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