Royals vs Red Sox Prediction, Picks & Odds — Wednesday, August 6

Ducey's prediction: Go for the Over as the Red Sox look to maintain their dominance at home in their finale against the Royals.

Kenny Ducey - Contributor at Covers
Kenny Ducey • Betting Analyst
Aug 6, 2025 • 15:52 ET • 4 min read
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This article contains predictions for an old game!

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Michael Wacha Kansas City Royals MLB
Photo By - Imagn Images. Kansas City Royals starting pitcher Michael Wacha (52) throws.

The Boston Red Sox have caught fire of late, winning nine out of their last 11 games which is a stretch that dates back to their series win over the Los Angeles Dodgers in late July. Now, they’ll look to secure a sweep of the Kansas City Royals at home on Wednesday.

We’ll explain in our Royals vs. Red Sox predictions how Boston should be set up to continue flexing its muscles at the plate while its newly-acquired starter could be in an extended period of trouble.

Without further ado, let’s hand out some MLB picks for Wednesday, August 6.

Royals vs Red Sox prediction

My Royals vs Red Sox best betOver 8.5 (-112 at DraftKings)

At this point, it’s hard to say the jury’s still out on late-career Michael Wacha. All the righty has done is pitch to an ERA under 3.40 for a fourth straight season, and he’s continuing to do so by inducing soft contact in the air with few walks against him.

The benefit, of course, is that the Kansas City Royals’ outfield defense is one of the best in baseball, and their park’s large dimensions help keep the ball in the park for Kansas City’s gloves to go to work.

Now, the righty has only grown stronger as the year’s gone on. He posted a season-best .238 Expected Batting Average in July with a slightly elevated .419 Expected Slugging, but the latter has always posed something of a problem for Wacha – which is why pitching at home is always a plus.

The right-hander carries a 4.10 road ERA into this start with a 2.63 ERA at home, and Boston’s small home park may wind up costing this fly-ball maestro on a couple of occasions.

On the other side of the coin, life should really be difficult for Dustin May as a ground-ball pitcher entering one of the worst teams in the league when it comes to defending in the infield.

Boston’s failed to support these types of pitchers for multiple years now as they search for answers all around the diamond, and May will be hoping to start finding more strikeouts to remove the variables that come along with batted balls on the ground.

He's done a slightly better job of that of late, striking out 22 in 21 1/3 innings last month, but he’ll meet a Royals team here which has struck out in just 18.5% of plate appearances while posting a beefy .214 Isolated Power in the last two weeks.

Kansas City ranks an impressive 12th in OPS to ground-ball arms which is seven spots higher than the reverse split, while Boston sits third against fly-ball pitchers.

It’s a dream matchup for both sides, really, and while the Boston Red Sox continue to rake, the Royals have made a sudden resurgence in the last 14 days in ranking 13th in wRC+.

I believe in both lineups here, particularly with Wacha stepping away from the sanctity of his home ballpark and into a tough environment against a team which has done a ton of slugging of late.

Royals vs Red Sox same-game parlay (SGP)

Over 8.5

Alex Bregman 2+ total bases

Michael Wacha Under 1.5 walks allowed

We’ll kick things off here with Alex Bregman, who’s cooled off a bit of late but is just a couple of games removed from a two-hit performance.

He’s done an exceptional job of hitting fly-ball pitchers like Wacha this season, running a .304 average next to a robust .589 slugging percentage, and in his six at-bats versus the righty in his career owns a .386 xBA and .551 xSLG.

I’m also pretty cool on the Red Sox’ ability to work counts in this one, as they carry a measly 7.6% walk rate into this one over the last two weeks.

Wacha is a master of control, and he’s now walked just two batters in his last three starts – extending his stretch of hitting the Under on this prop in 11 of his last 18 outings.

I expect Boston to rip the ball against the righty, but I don’t expect it to sit around and wait at the dish in a matchup like this.

Royals vs Red Sox odds

Royals vs Red Sox live odds

Royals vs Red Sox opening odds

  • Moneyline: Kansas City +116 | Boston -134
  • Run line: Kansas City +1.5 (-170) | Boston -1.5 (+140)
  • Over/Under: Over 9 | Under 9

Royals vs Red Sox trend

The Kansas City Royals have covered the Run Line in 33 of their last 46 away games (+17.30 Units / 25% ROI). Find more MLB betting trends for Royals vs. Red Sox.

How to watch Royals vs Red Sox and game info

Location Fenway Park, Boston, MA
Date Wednesday, August 6, 2025
First pitch 7:10 p.m. ET
TV FanDuel Sports Network-Kansas City, NESN
Royals starting pitcher Michael Wacha
(5-9, 3.38 ERA)
Red Sox starting pitcher Dustin May
(6-7, 4.85 ERA)

Royals vs Red Sox latest injuries

Royals vs Red Sox weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Kenny Ducey - Covers
Betting Analyst

Kenny Ducey has worked in sports media for more than 10 years and began his journey as a credentialed reporter with Fordham University's WFUV Sports before moving on to Sports Illustrated. There, he wrote about baseball, basketball, and tennis - twice covering the NBA Finals.

He's been in the betting space for seven years, and has established himself as a top expert in MLB and tennis handicapping with brands like Tennis Channel, NBC Sports, and DraftKings. He's also been a frequent guest on betting shows such as MLB's Bettor's Eye and Tennis Bets Live.

Kenny has a knack for identifying underappreciated pitchers and tennis players as moneyline underdogs and credits his unique data analysis and hours of watching sports as the biggest reasons for success through the years. His best advice to bettors? Watch the games, trust your eye, and always question the public narrative.

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