Nationals vs Astros Prediction, Picks & Odds — Wednesday, July 30

The Astros snapped out of a funk with a 7-4 win over the Nationals on Tuesday night. Christian Walker's bat and Ryan Gusto's arm will help make that two in a row this afternoon.

Ryan Gilbert - Contributor at Covers.com
Ryan Gilbert • Betting Analyst
Jul 30, 2025 • 08:06 ET • 4 min read
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This article contains predictions for an old game!

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Christian Walker Houston Astros MLB
Photo By - Imagn Images. Astros 1B Christian Walker drilling a base hit vs. the Nationals.

The Houston Astros got back on track with a win on Tuesday night and host the Washington Nationals for the rubber game of their series this afternoon.

My Nationals vs. Astros predictions expect the home squad to make it back-to-back wins in our best MLB picks on Wednesday, July 30.

Nationals vs Astros prediction

My Nationals vs Astros best bet: Astros moneyline (-120 at FanDuel)

The Houston Astros were in a rut for the better part of the past week, with just eight runs scored during their five-game losing streak to the Athletics and Washington Nationals. However, they finally broke out for 13 hits in a 7-4 victory over Washington. 

Houston is now 61-47 on the season and 34-24 at home. Eight different Astros players recorded a hit on Tuesday night, which should be a sign of things to come.

MacKenzie Gore is the best the Nationals can throw at the Astros, but in his two starts since the All-Star break, he allowed eight runs on eight hits in 2.1 innings, then danced around six walks in five innings against the Twins.

Ryan Gusto is getting the start for the Astros, and although he got beat up by the Athletics last time out, Houston's bullpen is one of the best in the league, while Washington's ranks dead last with a 5.63 ERA.

Nationals vs Astros same-game parlay (SGP)

Astros moneyline

Ryan Gusto 4+ strikeouts

Christian Walker 2+ total bases

Gusto averages just over a strikeout per inning this season (82 Ks in 80 IP), and has reached this four-strikeout mark in nine of his 13 starts. He had five strikeouts last time out, even with the A’s beating him up a bit.

Christian Walker went 2-for-4 on Tuesday to reach a modest four-game hitting streak. He's had two total bases in three of those, and is 2-for-6 against Gore in his career.

Nationals vs Astros odds

Nationals vs Astros live odds

Nationals vs Astros opening odds

  • Moneyline: Washington +100 | Houston -120
  • Run line: Washington +1.5 (-205) | Houston -1.5 (+170)
  • Over/Under: Over 7.5 (-120) | Under 7.5 (+100)

Nationals vs Astros trend

The Houston Astros have hit the Moneyline in 44 of their last 73 games (+8.85 Units / 9% ROI). Find more MLB betting trends for Nationals vs. Astros.

How to watch Nationals vs Astros and game info

Location Daikin Park, Houston, TX
Date Wednesday, 7-30-2025
First pitch 2:10 p.m. ET
TV MASN, SCHN
Nationals starting pitcher MacKenzie Gore
(4-10, 3.52 ERA)
Astros starting pitcher Ryan Gusto
(6-4, 5.18 ERA)

Nationals vs Astros latest injuries

Nationals vs Astros weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Ryan Gilbert - Covers
Betting Analyst

Ryan Gilbert brings the passion and pain of being a Philadelphia sports fan. After graduating from Monmouth University with a finance degree, he now uses his statistical background to find inefficiencies in betting markets. With past stops at NHL.com, NBC Sports, and currently at Covers, Ryan's hot picks blend well with the cold ice of a hockey rink.

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