Mariners vs Tigers Prop Picks & Best Bets for ALDS Game 4

Casey Mize gets a better strikeout matchup here than he did in his postseason debut last week, and the Over on the Tigers SP's strikeout market headlines our Mariners vs. Tigers Game 4 player props.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Oct 8, 2025 • 11:03 ET • 4 min read
Casey Mize Detroit Tigers MLB
Photo By - Imagn Images. Tigers SP Casey Mize (12) delivers a pitch.

The Detroit Tigers host the Seattle Mariners in Game 4 of the ALDS this afternoon. The Tigers have their backs against the wall with the M's up two games to one in this best-of-five series.

I'm expecting that desperation to lead to a strong performance from Detroit in a matchup against struggling Seattle starter Bryce Miller.

See how that factors into my MLB picks as I bring you my three favorite MLB player props and Mariners vs. Tigers predictions on Wednesday, October 8. 

Mariners vs Tigers Game 4 props

Player BetMGM
Tigers Casey Mize Over 3.5 strikeouts +115
Mariners Bryce Miller Over 1.5 earned runs -190
Tigers Riley Greene Over 1.5 total bases +125

Mariners vs Tigers player prop picks

Prop #1: Casey Mize Over 3.5 strikeouts

+115 at BetMGM

Detroit Tigers right-hander Casey Mize generated just one strikeout in three innings in his postseason debut last week.

That said, the starter ended the season with some strong performances. He fanned 29 batters in 23 1/3 innings over his last four regular-season starts, which included three outings of 8+ strikeouts. 

The Seattle Mariners have been hitting for power significantly better on the road, but are striking out at a high rate regardless of the venue. The M's are 23rd in the majors in strikeout rate (23.4%) while ranking 28th in whiff rate.

Prop #2: Bryce Miller Over 1.5 earned runs

-190 at BetMGM

Bryce Miller has been terrible this year, sitting in the Bottom 10th percentile in expected ERA (5.29) and expected batting average (.285) while posting the worst average exit velocity among all qualifying pitchers. 

Miller will face a desperate Tigers squad that was third in the AL in OPS (.769) and runs per game (4.91) at home during the regular season. 

The righty likely won't pitch deep into this contest, but the O/U on his earned runs still seems off at 1.5. He has surrendered 2+ runs in each of his last 12 starts, pitching to a 6.79 ERA over that span.

Prop #3: Riley Greene Over 1.5 total bases

+125 at BetMGM

Miller gets hit hard, especially by left-handed hitters who slug .530 against him. That's bad news against Tigers outfielder Riley Greene, who finished the regular season with 296 total bases (16th in MLB).

Greene slugged .563 with the platoon advantage, and he'll benefit from home-field advantage today. He also makes excellent contact against four-seamers, splitters, and curveballs, and those pitches make up 85% of Miller's offerings against lefties. 

How to watch Mariners vs Tigers and Game 4 info

Location Comerica Park, Detroit, MI
Date Wednesday, October 8, 2025
First pitch 3:08 p.m. ET
TV FS1

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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