MLB Home Run Predictions Today: Best HR Prop Bets, Picks, Parlay & Odds for Sunday, June 21

Chris Faria - Contributor at Covers.com
Chris Faria • Betting Analyst 8+ years betting experience
Updated: Jun 21, 2026 , 08:49 AM ET • 4 min read

Brandon Lowe is among Chris Faria's best bets to go deep today.

Brandon Lowe Pirates MLB
Photo By - Reuters Connect. Brandon Lowe of the Pittsburgh Pirates.

There are plenty of mismatches on today’s MLB schedule, and some value to be found on MLB home run props.

My MLB player props for Sunday, June 21 include Brandon Lowe and James Wood.

Read on for my full analysis.

Best MLB home run props today

Player to hit a HR Odds
Pirates Brandon Lowe +218
Nationals James Wood +288
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Home run pick: Brandon Lowe (+218)

Coors Field is the most homer-friendly venue in the majors with a 112 Park Factor, and Brandon Lowe will have plenty of opportunity to go yard this afternoon.

The Pittsburgh Pirates second baseman has hit 14 of his 18 dingers vs. right-handed pitching, and Colorado Rockies starter Michael Lorenzen provides a favorable matchup.

Lefties like Lowe are batting .403 vs. Lorenzen this season, while the 34-year-old has surrendered 1.5 HR/9.

The Rockies bullpen has also been susceptible to the long ball, giving up 44 homers this year — tied for third most in MLB.

I’m playing Lowe up to +210.

  • Time: 3:10 p.m. ET
  • Where to watch: SportsNet Pittsburgh, Rockies.TV

Home run pick: James Wood (+288)

James Wood hit 31 dingers last season, but the 23-year-old is already up to 20 home runs in what’s shaping up to be a true breakout year.

The Washington Nationals slugger ranks among the top percentile in the majors in xSLG, average exit velocity, and barrel %, so it’s no surprise how often he’s going yard.

Tampa Bay Rays starter Nick Martinez has given up 1.7 HR/9 over his last three appearances, while the team’s bullpen has allowed 47 dingers – second-most among all clubs.

Wood provides solid value at anything north of +275.

  • Time: 1:40 p.m. ET
  • Where to watch: Nationals.TV, Rays.TV
Chris Faria's 2026 Transparency Record
  • HR picks: 8-24, +1.82 units

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Chris Faria - Covers
Betting Analyst

After writing a few pieces for the Varsity newspaper during his time at the University of Toronto, Chris Faria's career in sports truly began in 2019 when he attended the sports journalism program at Centennial College. Since then, he’s covered virtually every sport under the sun, having written for several different outlets including Covers and the Canadian Olympic Committee. A lifelong hockey fan and player, Chris currently works full-time for the National Hockey League.

Outside of hockey, he’s also an avid poker player and mixed martial arts fan, which is coincidentally his favorite sport to bet on – usually in the form of a parlay on bet365. The main lesson he’s learned from years of betting is bankroll management: "Never bet more than you’re comfortable losing and never chase your losses."

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