Dodgers vs Guardians Prediction, Picks & Odds for Today’s MLB Game

The Dodgers have taken the Guardians' two best starters to the cleaners and Cleveland hasn't even announced an SP for this afternoon. We like LA to finish the sweep, again winning by multiple runs.

Eric Rosales - Contributor at Covers.com
Eric Rosales • Betting Analyst
May 28, 2025 • 08:55 ET • 4 min read
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This article contains predictions for an old game!

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Clayton Kershaw Los Angeles Dodgers MLB
Photo By - Imagn Images. Dodgers LHP Clayton Kershaw gets ready to deliver a pitch.

The Los Angeles Dodgers have the brooms ready as they seek a three-game sweep of the Cleveland Guardians this afternoon at Progressive Field.

With veteran Clayton Kershaw on the bump to close things out, and Cleveland’s starting pitching situation in flux (more on that below), our Dodgers vs Guardians predictions have the visitors taking care of business again in the finale.

Check our free MLB picks for Wednesday, May 28.

Dodgers vs Guardians prediction

My Dodgers vs Guardians best bet: Dodgers -1.5 (+115 at Caesars)

The Los Angeles Dodgers are a Top-3 scoring unit in baseball, averaging 5.57 runs per game, and they’ve battered Cleveland Guardians pitching through two games, outscoring them 16-7, including Tuesday’s 9-5 win.

The Dodgers are an offensive juggernaut. They rank first in team batting average at .264 and second in on-base percentage, slugging percentage, and OPS.

That’s helped cover up a pitching staff that's 19th in the majors in team ERA at 4.03.

Today, veteran Clayton Kershaw will get the call, making only his third start of the year as he’s slowly recovering from toe and knee surgeries in the offseason. Rain ended his last outing against the Mets as he tossed only 26 pitches over two innings without giving up a hit or run and striking out one.

Cleveland has lost three straight after reeling off four wins in a row. It’s been all or nothing for the Guardians, and right now, they’re in the nothing part.

Scoring has been a problem during this latest slide, as Cleveland has only put up seven runs across three games. On the year, the team is 23rd with 3.98 runs per game.

Pitching might also be an issue, as scheduled starter Slade Cecconi will miss his start because of groin tightness.

As of early Wednesday morning, manager Stephen Vogt has not yet named a replacement.

However, it might not matter. The Dodgers are chasing the Tigers and Phillies for the best record in baseball, and they have beaten Cleveland in four straight and six of the last seven.

Even a decent Kershaw performance should be boosted by an offense that continues to mash the baseball.

Dodgers vs Guardians same-game parlay (SGP)

Dodgers -1.5

Dodgers team total Over 5.5

Guardians team total Under 3.5

Since April 26, LA is 18-11, and of those victories, it scored six runs or more in 15 of them. As we’re taking the Dodgers to sweep the Guardians, expect to see another healthy run total in the series finale.

We’ll wrap with a flier on Kershaw putting in a good start for his first real contribution to the Dodgers this season.

He was chased by the Angels in just four innings of work, giving up five hits and five earned runs in his one true start of the season.

But Kershaw is a legend, a three-time Cy Young winner with a career ERA of 2.51. Against the weak-hitting Guardians, this is the perfect tune-up opportunity.

Dodgers vs Guardians odds

Dodgers vs Guardians live odds

Dodgers vs Guardians opening odds

  • Moneyline: Los Angeles -135 | Cleveland +115
  • Run line: Los Angeles -1.5 (+122) | Cleveland +1.5 (-145)
  • Over/Under: Over 9 (-110) | Under 9 (-110)

Dodgers vs Guardians trend

Cleveland has lost eight straight day games vs NL West teams with a winning record. Find more MLB betting trends for Dodgers vs. Guardians.

How to watch Dodgers vs Guardians and game info

Location Progressive Field, Cleveland, OH
Date Wednesday, 5-28-2025
First pitch 1:10 p.m. ET
TV SportsNet LA, CLEG
Dodgers starting pitcher Clayton Kershaw
(0-0, 7.50 ERA)
Guardians starting pitcher TBD

Dodgers vs Guardians latest injuries

Dodgers vs Guardians weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Eric Rosales - Covers
Betting Analyst

Eric has been involved in sports media in many different capacities since graduating from journalism school in 1999, back when getting your own column in a newspaper was still considered a thing. He doubled down and graduated from broadcast journalism school five years later, which led to a move to Toronto and a career with The Sports Network (TSN). From behind-the-scenes production work, he moved into the digital realm, where he had his own hoops column (At the Buzzer), while regularly live streaming and chatting with fans during broadcasts as the character known as LeBlog James. He was also a key contributor to TSN and CTV’s Olympic programming during the 2012 London Games.

Eric eventually found his way into the sports betting field in 2016 and has been a mainstay ever since. He was tagged on Twitter as a Top 10 NBA sharp during the 2021 season and has been interviewed about basketball and his handicapping process on shows from Vancouver to India. Eric is now a jack-of-all-sports at Covers, where his predictions span the alphabet soup: NFL, NBA, MLB, NHL, F1, WNBA, Euro, and Copa.

When making picks, he focuses on finding value first and foremost, and ensuring readers have all the information they need to make an informed choice.

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