First place is at stake in the NL West as the Dodgers meet the Padres in San Diego. Game 1 of the series saw the lead switch hands, as the Padres are now in front by a half game.
The 1-0 loss by L.A. is the only blemish on either team’s record over the last five days.
A favorable starting pitching matchup has my Dodgers vs. Padres predictions and MLB picks looking for the Dodgers to take back the top spot with a road win on Tuesday, May 19.
Who will win Dodgers vs Padres today: Dodgers moneyline (-155)
The San Diego Padres have won four straight and five of their last six, while the Los Angeles Dodgers saw a five-game win streak snapped thanks to their NL West rival. L.A. also saw a temporary halt to its offensive rebirth.
Prior to the shutout loss, the Dodgers had scored 36 runs in four games. Shohei Ohtani appears to be shaking off an early season slump. He went 2-for-3 Monday and is 8 for his last 16. They’ll try to keep it going against Griffin Canning and his 10.64 ERA.
Dodgers pitching has allowed just six runs in the last six games and they'll go with Emmet Sheehan on the mound tonight who has won his last two starts.
COVERS INTEL: Canning has allowed more than 12 hits per nine, but some of that is hard luck. He’s allowing .452 BABIP, and his FIP (predictor of true ERA) is just 4.19. He’s walking 7.4 per nine, however, which is problematic.
Dodgers vs Padres Over/Under pick: Under 8.5 (-115)
There will likely be more scoring than in the 1-0 series opener, but the Dodgers have been dominant on the mound recently.
Over the last week, opponents are hitting .194 with .567 OPS against L.A. and are collectively producing at 37% below league average at the plate. The pen is well-rested with just two relievers throwing a total of 19 pitches over the last two days.
The Padres have been almost as good, allowing .208 average and .575 OPS over the last two weeks, producing opposing offense 33% below league average. The San Diego bullpen is a little more fatigued than the Dodgers’, which could be an issue if Canning struggles early.
- ML/RL bets: 13-19 -5.33 units
- Over/Under bets: 18-18 -1.51 units
Dodgers vs Padres odds
- Moneyline: Los Angeles -155 | San Diego +140
- Run line: Los Angeles -1.5 (+100) | San Diego +1.5 (-122)
- Over/Under: Over 8.5 (+104) | Under 8.5 (-127)
Dodgers vs Padres trend
The Los Angeles Dodgers have only hit the Game Total Over in 19 of their last 45 games (-9.85 Units / -20% ROI). Find more MLB betting trends for Dodgers vs. Padres.
How to watch Dodgers vs Padres and game info
| Location | Petco Park, San Diego, CA |
| Date | Tuesday, May 19, 2026 |
| First pitch | 9:40 p.m. ET |
| TV | SNLA, Padres.TV |
| Dodgers starting pitcher | Emmet Sheehan (3-1, 4.54 ERA) |
| Padres starting pitcher | Griffin Canning (0-2, 10.64 ERA) |
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Odds are correct at the time of publishing and are subject to change.
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