Diamondbacks vs Dodgers Prediction, Odds & Home Run Pick for Tonight's MLB Game

JD Yonke - Betting Analyst at Covers.com
JD Yonke • Betting Analyst 7+ years betting experience
Updated: Mar 26, 2026 , 09:46 AM ET • 4 min read

Our Diamondbacks vs. Dodgers predictions don't expect Kyle Tucker to waste any time on his new squad.

MLB

Match starts: 9 hrs
AZ
33 %
LAD
67 %
EXPERT PICK - PROP
Kyle Tucker o0.5  Total RBIs (+145) Kyle Tucker o0.5 Total RBIs (+145)
Read Analysis
Kyle Tucker Los Angeles Dodgers MLB
Photo By - Reuters Connect. Kyle Tucker slides into home against the Diamondbacks.

The reigning World Series Champions begin their title defense as the Los Angeles Dodgers host the Arizona Diamondbacks on Opening Day.

The game will be broadcast on NBC and Peacock at 8:30 pm ET as part of the network’s Opening Day doubleheader. 

My Diamondbacks vs. Dodgers predictions and MLB picks are targeting Kyle Tucker for my best bet.

Diamondbacks vs Dodgers predictions

Diamondbacks vs Dodgers best bet: Kyle Tucker Over 0.5 RBI (+145)

The newly acquired Kyle Tucker is a sharp bet to lead the National League in RBI. He’ll have a premium lineup position in the top-third of the best lineup in baseball, and is projected to hit behind Shohei Ohtani (.392 OBP). 

Arizona Diamondbacks starter Zac Gallen had an unsightly 4.83 ERA last year and ranked 42nd out of 47 qualified starters in Stuff+ (93). He didn’t look any better in Spring Training (7.59 ERA and 1.78 WHIP).

Tucker has had success in this matchup, going 6-for-18 with five RBI in his career against the right-hander.

Covers COVERS INTEL: Kyle Tucker has strong plate discipline, ranking in the 96th percentile in walk rate (14.6%) and the 98th percentile in chase rate (17.6%). Gallen had a poor 10.5% K-BB% against lefties in 2025, so he’ll likely pitch to contact.

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Diamondbacks vs Dodgers same-game parlay (SGP)

Arizona finished 80-82 last year and didn’t have a particularly inspirational offseason. 

The Los Angeles Dodgers send out the World Series MVP, Yoshinobu Yamamoto, to the bump, giving them a big leg up in the pitching department. The projected Arizona lineup has a measly .450 OPS against the Japanese hurler.

There aren’t a lot of whiffs in the 2026 version of this Dodgers lineup. Tucker’s 14.7% K-rate from a season ago fits right in with low-strikeout bats like Mookie Betts, Freddie Freeman, and Miguel Rojas. Gallen’s K-rate has steadily declined since his debut and was down to 21.5% a year ago.

Diamondbacks vs Dodgers SGP

  • Dodgers moneyline
  • Zac Gallen Under 4.5 strikeouts
  • Kyle Tucker Over 0.5 RBI

Diamondbacks vs Dodgers home run pick: Max Muncy (+400)

Max Muncy, the longest tenured Dodger on this year’s roster, has had issues staying on the field, but he typically rakes when healthy.

Well, he certainly looked healthy in spring (.333/.429/.583 with three homers), and it’s a plus matchup against Gallen. Lefties crushed the veteran (1.37 WHIP) a year ago as he struggled to find the right out pitch. 

Muncy posted a 164 wRC+ and blasted 15 of his 19 home runs at Dodger Stadium in 2025.

Diamondbacks vs Dodgers odds

  • Moneyline: Arizona +220 | Los Angeles -270
  • Run line: Arizona +1.5 (+110) | Los Angeles -1.5 (-125)
  • Over/Under: Over 9 | Under 9

Diamondbacks vs Dodgers trend

The Dodgers cashed their team total Over in 22 of their 35 final games last season. Find more MLB betting trends for Diamondbacks vs. Dodgers.

How to watch Diamondbacks vs Dodgers and game info

Location Dodger Stadium, Los Angeles, CA
Date Thursday, March 26, 2026
First pitch 8:30 p.m. ET
TV NBC
Diamondbacks starting pitcher Zac Gallen
(2025: 13-15, 4.83 ERA)
Dodgers starting pitcher Yoshinobu Yamamoto
(2025: 12-8, 2.49 ERA)

Diamondbacks vs Dodgers latest injuries

Diamondbacks vs Dodgers weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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JD Yonke
Betting Analyst

JD is a diehard college football fan with five years of experience writing betting and fantasy content for publications such as SportsGrid, Fantasy Points, Fantrax, and Devy Watch. An avid reader, he uses his inclination to look at things with an exhausting and in-depth, analytic viewpoint combined with a love for statistics and metrics to form a well-rounded handicapping approach.

e's an integral member of the niche (but growing!) college fantasy football community, twice traveling to Canton, OH for the Fantasy Football Expo as a member of the CFF King's Classic drafting squad. His specialization in college football DFS and prop betting taught him that there are exploitable markets to be found and that narrowing your focus is integral to being a profitable bettor.

A lifelong Californian who grew up playing baseball, basketball, football, and lacrosse, he's glad to share a passionate love for sports with this wonderful community.

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