The Milwaukee Brewers and Chicago Cubs will finish up a busy day when they play the second game of their doubleheader at Wrigley Field tonight.
Milwaukee has been outstanding as of late, and I’m taking it to finish off a doubleheader sweep in my Brewers vs. Cubs predictions.
Let’s take a look at why I like the Brewers for tonight’s game in my free MLB picks for Monday, August 18.
Cubs vs Brewers Game 2 prediction
Cubs vs Brewers best bet: Brewers moneyline (-105)
The Milwaukee Brewers have been on an absolute heater and have pretty much run away with the NL Central race, leaving the Chicago Cubs nine games back after winning today's first game 7-0.
Right now, it’s hard to bet against Milwaukee, which has a +168 run differential — by far the best mark in the majors.
It would take a massive pitching mismatch in Chicago’s favor for me to take the Cubs tonight, and that’s not what we have here. Rookie Chad Patrick hasn’t gone deep in games for the Brewers, but he has a 3.52 ERA over his first 94 2/3 innings of work at the Major League level, striking out a batter per inning and posting a respectable 1.29 WHIP.
Based on reputation, the Cubs might think they have the edge by starting Jameson Taillon. But the 33-year-old hasn’t been great in 2025, as he’s allowing too many homers — 2.1 per nine innings — which has seen his ERA balloon to 4.44 on the season.
Chicago has lost Taillon’s last three starts, and he hasn’t gone even five innings in any of those games. That’s a matchup that the red-hot Brewers can handle. I’m taking Milwaukee to win outright in the nightcap.
Caesars QuickPick: Our Cubs vs Brewers Game 2 same-game parlay (SGP)
I like the Brewers to win this one, but I think the total is set a little too high at nine full runs, even with both teams having their pitching strained.
I see the Under as the smart play tonight. I’ll also take William Contreras to pick up a RBI tonight, something he’s done in six of his last nine games.
Cubs vs Brewers Game 2 odds
- Moneyline: Chicago -115 | Milwaukee -105
- Run line: Chicago -1.5 (+160) | Milwaukee +1.5 (-190)
- Over/Under: Over 9 | Under 9
Cubs vs Brewers Game 2 trend
The Brewers are 18-2 in their last 20 games overall. Find more MLB betting trends for Cubs vs. Brewers.
How to watch Cubs vs Brewers and game info
| Location | American Family Field, Milwaukee, WI |
| Date | Monday, August 18, 2025 |
| First pitch | 8:05 p.m. ET |
| TV | FDSN Wisconsin, Marquee |
| Cubs starting pitcher | Jameson Taillon (7-6, 4.44 ERA) |
| Brewers starting pitcher | Chad Patrick (3-7, 3.52 ERA) |
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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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