The Seattle Mariners host the Milwaukee Brewers in the opening matchup of this three-game series at T-Mobile Park, and my Brewers vs. Mariners predictions expect the Brew Crew to keep the good times rolling.
Find out why in my MLB picks for Monday, July 21.
Brewers vs Mariners prediction
My Brewers vs Mariners best bet: Brewers moneyline (+105 at Caesars)
The Milwaukee Brewers hand the ball to right hander Brandon Woodruff, who has been excellent since returning from injury. Woodruff was performing like a Cy Young candidate before injuring his shoulder in 2023, and he's picked up right where he left off.
Through two starts, the right-hander is 1-0 with a 2.61 ERA and 0.68 WHIP. His underlying metrics are even more dominant, as Woodruff boasts a 2.21 expected ERA (xERA) and .189 expected batting average (xBA).
Meanwhile, righty George Kirby takes the mound for the Seattle Mariners. It’s been the worst year of his career so far, with a 4.50 ERA and 1.15 WHIP through 10 starts.
His analytics are also concerning, as Kirby ranks in the bottom third of the league in xBA, average exit velocity, and hard-hit rate. The Brewers can take advantage of those pitching woes.
Entering this matchup, Milwaukee ranks in the top half of the league in runs scored per game, hits per game, batting average, and on-base percentage.
Caesars QuickPick: Our Brewers vs Mariners same-game parlay (SGP)
Brewers moneyline
Brandon Woodruff 7+ strikeouts
Caleb Durbin 1+ hit
Part of Woodruff’s early success has been his command. Although it’s a small sample size, he would rank first in Major League Baseball in both strikeout rate and walk rate if he qualified. He's recorded eight or more strikeouts in each of his first two starts.
Meanwhile, Caleb Durbin enters this contest in excellent form, with at least one hit in each of his past six games. He boasts a .409 batting average over that stretch.
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Brewers vs Mariners odds
Brewers vs Mariners live odds
Brewers vs Mariners opening odds
- Moneyline: Milwaukee -105 | Seattle -115
- Run line: Milwaukee +1.5 (-227) | Seattle -1.5 (+185)
- Over/Under: Over 7 | Under 7
Odds courtesy of Caesars.
Brewers vs Mariners trend
Milwaukee has won each of its past 10 games. Find more MLB betting trends for Brewers vs. Mariners.
How to watch Brewers vs Mariners and game info
| Location | T-Mobile Field, Seattle, WA |
| Date | Monday, 7-21-2025 |
| First pitch | 9:40 p.m. ET |
| TV | FDSNWI, RSNW |
| Brewers starting pitcher | Brandon Woodruff (1-0, 2.61 ERA) |
| Mariners starting pitcher | George Kirby (4-4, 4.50 ERA) |
Brewers vs Mariners latest injuries
Brewers vs Mariners weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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