Chicago Cubs shortstop Dansby Swanson draws one of the toughest matchups in baseball today against Dylan Cease, whose elite swing-and-miss arsenal should neutralize the struggling slugger.
Read on for my top Blue Jays vs. Cubs predictions and MLB picks for this Sunday, June 21 matchup.
Blue Jays vs Cubs predictions
Blue Jays vs Cubs best bet: Dansby Swanson Under 0.5 hits (-130)
Dansby Swanson has been one of the worst hitters in baseball this season with a .177 batting average, while ranking in the second percentile in xBA.
Additionally, his hitting profile does not match up well at all against Toronto Blue Jays starter Dylan Cease, who has elite swing-and-miss stuff.
Swanson can’t hit the breaking ball this season, owning a .095 average with a 33% whiff rate.
That won’t bode well against Cease, who ranks in the 99th percentile in strikeout rate with a 37% whiff rate.
A lot of his whiffs come from his slider, which is his most-used pitch to right-handed batters, which is also a pitch that Swanson struggles with (.048 batting average, 37% whiff rate).
Additionally, Swanson is just 1-for-6 against Cease in his career. I’d play this prop up to -140.

Blue Jays vs Cubs same-game parlay (SGP)
Cease has electric stuff, leading the American League with 110 Ks. He’s eclipsed today’s number in seven straight starts and owns a 39% strikeout rate against this Chicago Cubs lineup.
George Springer is turning a corner with a 1.089 OPS over his last nine games, and profiles well against Shota Imanaga, who’s primarily a fastball pitcher.
Springer owns a .291 xBA over the last three seasons with a .613 xSLG.
Blue Jays vs Cubs SGP
- Dansby Swanson Under 0.5 hits
- Dylan Cease Over 6.5 strikeouts
- George Springer Over 1.5 total bases
Blue Jays vs Cubs home run pick: Kazuma Okamoto (+365)
Kazuma Okamoto's hitting profile matches up perfectly against Imanaga’s stuff.
The Cubs starter throws a heavy dose of the fastball and gets barreled up at a 10.4% rate. The Jays third baseman barrels the ball better than anyone in the Blue Jays lineup (13.5%) while possessing a 63.2% hard-hit rate against the four-seamer.
Additionally, Imanaga has allowed 14 home runs over 15 outings this season.
This is a half-unit wager.
- Best bets: 35-39, +0.75 units
- SGPs: 14-60, +2.15 units
- HR picks: 12-62, +1.8 units
Blue Jays vs Cubs odds
- Moneyline: Toronto -116 | Chicago +102
- Run line: Toronto -1.5 | Chicago +1.5
- Over/Under: Over 7 | Under 7
Blue Jays vs Cubs trend
The Blue Jays have hit the moneyline in nine of their last 14 away games (+6.00 Units / 41% ROI). Find more MLB betting trends for Blue Jays vs. Cubs.
How to watch Blue Jays vs Cubs and game info
| Location | Wrigley Field, Chicago, IL |
| Date | Sunday, 6-21-2026 |
| First pitch | 2:20 p.m. ET |
| TV | MARQ, Sportsnet |
| Blue Jays starting pitcher | Dylan Cease (4-3, 2.71 ERA) |
| Cubs starting pitcher | Shota Imanaga (4-6, 4.26 ERA) |
Blue Jays vs Cubs latest injuries
Blue Jays vs Cubs weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.






