Vladimir Guerrero Jr. is swinging a hit bat right now, and my Blue Jays vs. Angels predictions expect him to remain hot tonight in a plus-matchup against Jack Kochanowicz.
Find out more in my MLB picks for Tuesday, April 21.
Blue Jays vs Angels predictions
Blue Jays vs Angels best bet: Vladimir Guerrero Jr. O 1.5 total bases (+110)
You’re getting great value on Vladimir Guerrero Jr. at +110 to go Over his bases total tonight.
He has been one of the most consistent hitters in baseball this season, batting .354, the second-highest average in the majors.
Vladdy is also currently riding an 11-game hitting streak, averaging 2.54 bases per contest in that stretch.
Additionally, Guerrero Jr. has faced Angels starter Jack Kochanowicz three times in his career, going 2-for-3 against him.
Kochanowicz primarily uses his sinker against right-handed batters with a 43% usage. That’ll be dangerous against Vladdy, who owns a .444 average against the pitch with a 56% hard-hit rate.
COVERS INTEL: Guerrero Jr. owns a 1.136 OPS during this current 11-game hitting streak. 
Blue Jays vs Angels same-game parlay (SGP)
I’ll continue to bank on the Toronto Blue Jays’ offense remaining hot and take the suddenly surging Nathan Luke’s to keep swinging the bat well by taking Over 0.5 hits. After an abysmal start, Luke’s has totalled eight hits while on a current four-game hitting streak. He is also 1-for-2 against Kochanowicz in his career.
For the last leg of the SGP, I’ll take Over 1.5 walks for Kochanowicz. The Los Angeles Angels righty has struggled right he zone this season, going Over the total in each of his four starts. He is also averaging 3.75 walks per game this season, which ranks in the 13th percentile in walk-rate among all pitchers.
Blue Jays vs Angels SGP
- Guerrero Jr. Over 1.5 total bases
- Lukes Over 0.5 hits
- Kochanowicz Over 1.5 walks
Blue Jays vs Angels home run pick: Vladimir Guerrero Jr. (+600)
I’ll make this a half-unit wager.
Kochanowicz is a ground-ball pitcher who doesn’t give up many homers — just one on the year.
However, Guerrero Jr. has been known to hit his homers in bunches, so I’ll bet on him getting another one tonight in Angel Stadium after going yard last night.
Additionally, Vladdy does seem to torture sinker ballers. He has a 56.6% hard-hit rate against the pitch this season, while posting a .532 slug-rate against it in 2025.
- Best bets: 5-16, -8.35 units
- SGPs: 2-19, -11.50 units
- HR picks: 4-17, +0.15 units
Blue Jays vs Angels odds
- Moneyline: Toronto +101 | Los Angeles -110
- Run line: Toronto +1.5 (-200) | Los Angeles -1.5 (+150)
- Over/Under: Over 9 | Under 9
Blue Jays vs Angels trend
The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 18 of their last 24 games (+12.20 Units / 42% ROI). Find more MLB betting trends for Blue Jays vs. Angels.
How to watch Blue Jays vs Angels and game info
| Location | Angel Stadium, Anaheim, CA |
| Date | Tuesday, April 21, 2026 |
| First pitch | 9:38 p.m. ET |
| TV | FDSN-W, SN1 |
| Blue Jays starting pitcher | Patrick Corbin (0-0, 4.66 ERA) |
| Angels starting pitcher | Jack Kochanowicz (2-0, 3.47 ERA) |
Blue Jays vs Angels latest injuries
Blue Jays vs Angels weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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