Astros vs Blue Jays Prediction, Odds & Home Run Pick for Today's MLB Game

Mike DiStefano - Contributor at Covers.com
Mike DiStefano • Betting Analyst 14+ years betting experience
Updated: Jun 23, 2026 , 01:24 PM ET • 4 min read

Expect Vladimir Guerrero Jr. to stay hot at the plate today.

MLB

Match starts: 1 hrs
HOU
46 %
TOR
54 %
EXPERT PICK - PROP
Kazuma Okamoto o0.5  Total Home Runs (+280) Kazuma Okamoto o0.5 Total Home Runs (+280)
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Toronto Blue Jays MLB Vladimir Guerrero Jr.
Photo By - Reuters Connect. Toronto Blue Jays first baseman Vladimir Guerrero Jr.

Toronto Blue Jays slugger Vladimir Guerrero Jr. is heating up and profiles well for continued success against Houston Astros starter Peter Lambert, making Over 1.5 total bases for Vladdy my favorite play tonight.

Read on for my Astros vs. Blue Jays predictions and MLB picks for this Tuesday, June 23 matchup.

Astros vs Blue Jays predictions

Astros vs Blue Jays best bet: Vladimir Guerrero Jr. Over 1.5 total bases (+105)

Toronto Blue Jays slugger Vladimir Guerrero Jr. profiles extremely well against Peter Lambert

The Houston Astros starter primarily throws a fastball/sinker/slider combination, which is a pitch mix that Vladdy has handled well this season, with a .314 batting average and a .331 BABIP.

Lambert has also allowed solid contact at a 7.5% rate, which is 1.6% above league average.

Guerrero Jr. is barreling the baseball more efficiently lately, too, which has seen an uptick in production over the last two weeks where he owns a .409 average and a .591 SLG.

Additionally, Guerrero Jr. has eclipsed this number in four of his last five games with a .526 SLG over this stretch, showing serious signs of a turnaround, which gives me confidence in his market.

I’d bet Guerrero Jr. Over 1.5 total bases down to +100. 

Covers COVERS INTEL: Guerrero ranks in the 94th percentile in xBA, and owns a 137 WRC+ over his last 20 at-bats.

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Astros vs Blue Jays same-game parlay (SGP)

George Springer is turning a corner, too, sporting a .351 average and 1.090 OPS over his last 10 games, recording a hit in eight of those outings. Additionally, he’s historically hit well against Lambert‘s pitch mix. 

I’ll also add Kazuma Okamoto Over 0.5 hits. He owns a .375 average against Lambert's pitches since June 1, while recording at least one hit in 13 of 18 games this month.

Astros vs Blue Jays SGP

  • Vladimir Guerrero Jr. Over 1.5 total bases
  • George Springer Over 0.5 hits
  • Kazuma Okamoto Over 0.5 hits
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Astros vs Blue Jays home run pick: Kazuma Okamoto (+280)

Okamoto profiles well against Lambert, who gives up a lot of solid contact, while ranking in the 48th percentile in hard-hit rate.

This all plays into Okamoto’s strengths, as he barrels the ball as well as anyone on the Jays roster and leads the team with 17 home runs while owning a .553 SLG and a 58.1% hard-hit rate against Lambert's pitch mix.

Additionally, Lambert has surrendered six home runs over his last seven-outings.

Despite the good matchup for Okamoto, the home run market is volatile, so I’ll make this a half-unit wager. 

2026 Transparency record
  • Best bets: 36-39, +2.15 units
  • SGPs: 14-61, +1.15 units
  • HR picks: 13-62, +2.9 units

Astros vs Blue Jays odds

  • Moneyline: Houston +112 | Toronto -132
  • Run line: Houston +1.5 | Toronto -1.5
  • Over/Under: Over 8.5 | Under 8.5

Astros vs Blue Jays trend

The Blue Jays have hit the Over in 13 of their last 21 games (+4.30 Units / 19% ROI). Find more MLB betting trends for Astros vs. Blue Jays.

How to watch Astros vs Blue Jays and game info

Location Rogers Centre, Toronto, ON
Date Tuesday, 6-23-2026
First pitch 4:07 p.m. ET
TV MLBN, SN
Astros starting pitcher Peter Lambert
(6-4, 3.23 ERA)
Blue Jays starting pitcher Shane Bieber
(2025: 4-2, 3.57 ERA)

Astros vs Blue Jays latest injuries

Astros vs Blue Jays weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Mike DiStefano - Covers
Betting Analyst

Mike DiStefano joins Covers after a successful five-year stint with TSN. Distefano hosted Leafs Lunch, a Toronto Maple Leafs-centric radio show which featured a daily best bets segment where he found the biggest and best value plays of the night. He was also a weekly staple on TSN's flagship radio/tv show "OverDrive" as a betting analyst during their NFL picks segment #TeamAl-DogForever.

A graduate of Centennial College’s Sports Journalism program, Mike has also contributed to the Canadian Baseball Network, FanSided, and The Hockey News.

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