Lions vs Roughriders Prediction, Picks & Odds for CFL Week 4

Ponnaiya's prediction: Bank on a low-scoring affair in Regina.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Jun 27, 2025 • 13:43 ET • 4 min read

CFL

Match starts: 21 hrs
SSK
76 %
BC
24 %
EXPERT PICK - TOTAL
u50.5 (-104)
Read Analysis
Rolan Milligan Saskatchewan Roughriders CFL
Photo By - Imagn Images. Saskatchewan Roughriders defensive back Rolan Milligan (0) makes a tackle.

The BC Lions head to Mosaic Stadium to face the Saskatchewan Roughriders on Saturday night.

Both teams will likely be playing without their star quarterbacks, which is why my Lions vs. Roughriders predictions are betting the Under on a lofty total.

Here are my best free CFL picks for this West Division showdown on June 28.

Lions vs Roughriders prediction

My Lions vs Roughriders pick: Under 50.5 (-110 at BET99)

The Saskatchewan Roughriders will start backup QB Jake Maier due to Trevor Harris suffering a head injury last week. Harris missed six games last season, and the Riders' offense struggled mightily in his absence.

BC Lions signal-caller Nathan Rourke will be a game-time decision but he took zero reps in practice yesterday, with Jeremiah Masoli and Chase Brice splitting first-team reps.

The key injuries for these attacks don't end there. The Riders will also be missing two of their top receivers in Samuel Emilus and Shawn Bane Jr., while the Leos’ already struggling offensive line will be without All-Star right tackle Dejon Allen.

It's also worth noting that these defenses are solid. The Riders have the top run defense in the CFL, holding foes to just 45.3 rushing yards per game on 3.4 yards per pop.

Although BC was gashed by Winnipeg's elite offense in Week 2, the Leos showed improvement against them last week and held Edmonton to 14 points in their season opener.

Lions vs Roughriders same-game parlay (SGP)

Under 50.5

Roughriders -2.5

Saskatchewan is 3-0 SU and ATS, and opened as 5.5-point favorites for this game.

The line has since moved below that key number of 3, which is an overreaction when you consider that BC will likely also be missing its top passer.

With the Riders boasting the superior defense and home-field advantage, back them to cover in a low-scoring battle. 

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Lions vs Roughriders odds

Lions vs Roughriders live odds

Lions vs Roughriders opening odds

  • Spread: BC +5.5 (-110) | Saskatchewan -5.5 (-110)
  • Moneyline: BC +195 | Saskatchewan -240
  • Over/Under: Over 51.5 (-110) | Under 51.5 (-110)

Lions vs Roughriders trend

Saskatchewan went 2-1 ATS against BC last year. Find more CFL betting trends for Lions vs. Roughriders.

How to watch Lions vs Roughriders and game info

Location Mosaic Stadium, Regina, SK
Date Saturday, 6-28-2025
Kick-off 7:00 p.m. ET
TV TSN

Lions vs Roughriders key injuries

Lions: Nathan Rourke QB (Questionable), Stanley Berryhill III WR (Out), Dejon Allen RT (Out), Jonah Tavai DT (Out).
Roughriders: Trevor Harris QB (Out), Shawn Bane Jr. WR (Out), Samuel Emilus WR (Out), Sean McEwan C (Out), Phillipe Gagnon G (Out), Kian Schaffer-Baker WR (Out), C.J. Avery LB (Out). 

Lions vs Roughriders weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than any analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics and Oscar odds. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez. You can catch Rohit breaking down every UFC event with Joe Osborne on "P4P Picks" on the Covers YouTube channel and he also has regular appearances on "Before You Bet" with Joe. In addition, he's a regular guest on "By The Book" on the Monumental Sports Network and makes guest appearances on VSIN's "The Handle" and CBS Sports. Rohit primarily makes his bets at bet365, which offers a wide variety of prop markets, but also has accounts at several others so he can shop around for the best prices. For Rohit, bankroll management is key. He believes you should never bet what you can't afford to lose and maximize those few betting opportunities where books misprice a line.

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