NFL
12/18/2025
07:27 ET
Bills @ Colts Picks & Props
BUF vs IND Picks
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BUF vs IND Consensus Picks
67% picking Buffalo
Total Picks BUF 1196, IND 583
BUF vs IND Props
Player
Prop
Season Avg.
Best Odds
BUF vs IND Trends
Buffalo Trends
The Buffalo Bills have hit the Moneyline in 15 of their last 22 games (+4.75 Units / 8% ROI)
BUF
IND
The Buffalo Bills have hit the 2Q Game Total Over in 15 of their last 19 games (+11.60 Units / 52% ROI)
Over
Under
The Buffalo Bills have hit the 3Q Moneyline in 11 of their last 19 games (+7.15 Units / 23% ROI)
BUF
IND
The Buffalo Bills have covered the 3Q Spread in 13 of their last 19 games (+6.70 Units / 30% ROI)
BUF
IND
The Buffalo Bills have hit the 2H Moneyline in 10 of their last 18 games (+3.10 Units / 10% ROI)
BUF
IND
The Buffalo Bills have hit the Team Total Over in 13 of their last 21 games (+4.10 Units / 17% ROI)
The Buffalo Bills have only hit the 4Q Moneyline in 5 of their last 19 games (-8.80 Units / -29% ROI)
BUF
IND
The Buffalo Bills have only hit the 1Q Moneyline in 7 of their last 22 games (-8.60 Units / -23% ROI)
BUF
IND
The Buffalo Bills have only hit the 2H Game Total Over in 6 of their last 18 games (-6.84 Units / -35% ROI)
Over
Under
The Buffalo Bills have only hit the Game Total Over in 3 of their last 11 away games (-5.90 Units / -48% ROI)
Over
Under
The Buffalo Bills have only hit the 1Q Game Total Over in 8 of their last 22 games (-8.20 Units / -32% ROI)
Over
Under
The Buffalo Bills have only covered the 1Q Spread in 9 of their last 22 games (-7.00 Units / -26% ROI)
BUF
IND
Indianapolis Trends
The Indianapolis Colts have hit the 1Q Game Total Over in 13 of their last 20 games (+5.90 Units / 26% ROI)
Over
Under
The Indianapolis Colts have covered the Spread in 13 of their last 20 games (+5.20 Units / 24% ROI)
BUF
IND
The Indianapolis Colts have covered the 3Q Spread in 6 of their last 8 games at home (+4.25 Units / 44% ROI)
BUF
IND
The Indianapolis Colts have hit the 4Q Game Total Under in 11 of their last 17 games (+4.15 Units / 21% ROI)
Over
Under
The Indianapolis Colts have hit the Moneyline in 7 of their last 10 games at home (+4.10 Units / 33% ROI)
BUF
IND
The Indianapolis Colts have only hit the 2Q Game Total Over in 5 of their last 17 games (-8.60 Units / -44% ROI)
Over
Under
The Indianapolis Colts have only hit the 4Q Game Total Over in 6 of their last 17 games (-6.65 Units / -34% ROI)
Over
Under
The Indianapolis Colts have only hit the 1H Game Total Over in 7 of their last 20 games (-6.55 Units / -29% ROI)
Over
Under
The Indianapolis Colts have only hit the 2H Game Total Over in 4 of their last 13 games (-6.02 Units / -41% ROI)
Over
Under
The Indianapolis Colts have only hit the 4Q Moneyline in 2 of their last 8 games at home (-4.15 Units / -43% ROI)
BUF
IND
The Indianapolis Colts have only hit the Team Total Over in 8 of their last 19 games (-4.40 Units / -20% ROI)
BUF vs IND Top User Picks
Buffalo Team Leaders
| Rank | Leader | L10 | Units |
|---|---|---|---|
| 1 | charro23 | 8-2-0 | +7420 |
| 2 | OOOPA LOOPA | 10-0-0 | +6200 |
| 3 | johnnyjbd24 | 7-3-0 | +5800 |
| 4 | dcrunk022 | 8-2-0 | +5350 |
| 5 | MillerBets54 | 9-1-0 | +5150 |
| 6 | Riverdawg | 9-1-0 | +4950 |
| 7 | Insiderone777 | 7-3-0 | +4750 |
| 8 | wgocts | 8-2-0 | +4700 |
| 9 | mccabe40 | 8-2-0 | +4550 |
| 10 | spiveytexas61 | 7-3-0 | +4550 |
| All Bills Money Leaders | |||
Indianapolis Team Leaders
| Rank | Leader | L10 | Units |
|---|---|---|---|
| 1 | bluetide007 | 8-2-0 | +6650 |
| 2 | AMERSPORTSREPORT | 6-3-1 | +6150 |
| 3 | kriskro | 6-3-1 | +5700 |
| 4 | fttrdoyle | 5-5-0 | +5200 |
| 5 | rcarr31 | 7-2-1 | +5200 |
| 6 | PaPe454 | 7-2-1 | +5150 |
| 7 | leafs126 | 8-1-1 | +4950 |
| 8 | cfox69 | 7-3-0 | +4850 |
| 9 | Barbarossa | 8-2-0 | +4800 |
| 10 | bryanoens | 7-3-0 | +4800 |
| All Colts Money Leaders | |||